Genome-Wide DNA Methylation Patterns of Bovine Blastocysts Developed In Vivo from Embryos Completed Different Stages of Development In Vitro
D Salilew-Wondim, E Fournier, M Hoelker… - PloS one, 2015 - journals.plos.org
Early embryonic loss and altered gene expression in in vitro produced blastocysts are
believed to be partly caused by aberrant DNA methylation. However, specific embryonic …
believed to be partly caused by aberrant DNA methylation. However, specific embryonic …
Genome-wide DNA methylation patterns of bovine blastocysts derived from in vivo embryos subjected to in vitro culture before, during or after embryonic genome …
D Salilew-Wondim, M Saeed-Zidane, M Hoelker… - BMC genomics, 2018 - Springer
Background Aberrant DNA methylation patterns of genes required for development are
common in in vitro produced embryos. In this regard, we previously identified altered DNA …
common in in vitro produced embryos. In this regard, we previously identified altered DNA …
Genome-wide screening of DNA methylation in bovine blastocysts with different kinetics of development
Background The timing of the first cell divisions may predict the developmental potential of
an embryo, including its ability to establish pregnancy. Besides differences related to …
an embryo, including its ability to establish pregnancy. Besides differences related to …
Embryo culture in presence of oviductal fluid induces DNA methylation changes in bovine blastocysts
AD Barrera, EV Garcia, M Hamdi… - 2017 - ri.conicet.gov.ar
During the transit through the oviduct, the early embryo initiates an extensive DNA
methylation reprogramming of its genome. Given that these epigenetic modifications are …
methylation reprogramming of its genome. Given that these epigenetic modifications are …
Aberrant DNA methylation in porcine in vitro‐, parthenogenetic‐, and somatic cell nuclear transfer‐produced blastocysts
AJ Bonk, R Li, L Lai, Y Hao, Z Liu… - Molecular …, 2008 - Wiley Online Library
Early embryonic development in the pig requires DNA methylation remodeling of the
maternal and paternal genomes. Aberrant remodeling, which can be exasperated by in vitro …
maternal and paternal genomes. Aberrant remodeling, which can be exasperated by in vitro …
Methylome Dynamics of Bovine Gametes and in vivo Early Embryos
DNA methylation undergoes drastic fluctuation during early mammalian embryogenesis.
The dynamics of global DNA methylation in bovine embryos, however, have mostly been …
The dynamics of global DNA methylation in bovine embryos, however, have mostly been …
Male fertility status is associated with DNA methylation signatures in sperm and transcriptomic profiles of bovine preimplantation embryos
J Kropp, JA Carrillo, H Namous, A Daniels, SM Salih… - BMC genomics, 2017 - Springer
Background Infertility in dairy cattle is a concern where reduced fertilization rates and high
embryonic loss are contributing factors. Studies of the paternal contribution to reproductive …
embryonic loss are contributing factors. Studies of the paternal contribution to reproductive …
Evaluation of genome-wide DNA methylation profile of human embryos with different developmental competences
M Yang, X Tao, K Scott, Y Zhan, RT Scott Jr… - Human …, 2021 - academic.oup.com
STUDY QUESTION Do embryos with different developmental competence exhibit different
DNA methylation profiles at the blastocyst stage? SUMMARY ANSWER We established …
DNA methylation profiles at the blastocyst stage? SUMMARY ANSWER We established …
An integrated platform for bovine DNA methylome analysis suitable for small samples
HA Shojaei Saadi, AM O'Doherty, D Gagné, É Fournier… - BMC genomics, 2014 - Springer
Background Oocytes and early embryos contain minute amounts of DNA, RNA and proteins,
making the study of early mammalian development highly challenging. The study of the …
making the study of early mammalian development highly challenging. The study of the …
Intragenic sequences in the trophectoderm harbour the greatest proportion of methylation errors in day 17 bovine conceptuses generated using assisted reproductive …
Background Assisted reproductive technologies (ART) are widely used to treat fertility issues
in humans and for the production of embryos in mammalian livestock. The use of these …
in humans and for the production of embryos in mammalian livestock. The use of these …