Many cancer cells rely on aerobic glycolysis for energy production and targeting of this
pathway is a potential strategy to inhibit cancer cell growth. In this study, inhibition of five …

Glycolysis can improve the tolerance of tissue cells to hypoxia, and its intermediates provide
raw materials for the synthesis and metabolism of the tumor cells. If it can inhibit the activity …

Glucose fermentation through glycolysis even in the presence of oxygen (Warburg effect) is
a common feature of cancer cells increasingly considered as an enticing target in clinical …

Most solid tumor cells adapt to their heterogeneous microenvironment by depending largely
on aerobic glycolysis for energy production, a phenomenon called the Warburg effect, which …

Background and Aim: The importance of glycolysis in cancer cells is well documented. The
effects of inhibiting glycolysis using metabolic inhibitors iodoacetate (IAA), an inhibitor of …

Background Novel therapeutic approaches are required to treat ovarian cancer and
dependency on glycolysis may provide new targets for treatment. This study sought to …

Metabolic change is one of the hallmarks of tumor, which has recently attracted a great of
attention. One of main metabolic characteristics of tumor cells is the high level of glycolysis …

Glucose, as the main consuming nutrient of the body, faces different destinies in cancer
cells. Glycolysis, oxidative phosphorylation, and pentose phosphate pathways produce …

Cancer is the second most important cause of death and new therapy modalities continue to
be developed and evolved. Cancer cells' metabolism is far different from the normal, healthy …

Most cancer cells exhibit increased glycolysis and use this metabolic pathway for generation
of ATP as a main source of their energy supply. This phenomenon is known as the Warburg …