Both severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East
respiratory syndrome coronavirus (MERS-CoV) are zoonotic pathogens that crossed the …

Coronaviruses (CoVs) have formerly been regarded as relatively harmless respiratory
pathogens to humans. However, two outbreaks of severe respiratory tract infection, caused …

Middle East respiratory syndrome coronavirus (MERS-CoV) infects humans from zoonotic
sources and causes severe pulmonary disease. Virions require spike (S) glycoproteins for …

Coronaviruses (CoVs) have a remarkable potential to change tropism. This is particularly
illustrated over the last 15 years by the emergence of two zoonotic CoVs, the severe acute …

Middle East respiratory syndrome coronavirus (MERS-CoV) is a newly identified
betacoronavirus causing high morbidity and mortality in humans. The coronavirus spike (S) …

Coronaviruses are a large group of enveloped, single-stranded positive-sense RNA viruses
that infect a wide range of avian and mammalian species, including humans. The …

Recent outbreaks of severe acute respiratory syndrome and Middle East respiratory
syndrome, along with the threat of a future coronavirus-mediated pandemic, underscore the …

Little is known about the biology of the emerging human group c betacoronavirus, Middle
East Respiratory Syndrome coronavirus (MERS-CoV). Because coronavirus spike …

Coronaviruses have frequently expanded their host range in recent history, with two events
resulting in severe disease outbreaks in human populations. Severe acute respiratory …

Receptor recognition is a major determinant of the host range, cross-species infections, and
pathogenesis of the severe acute respiratory syndrome coronavirus (SARS-CoV). A defined …