[HTML][HTML] Associations between sleep, cortisol regulation, and diet: Possible implications for the risk of Alzheimer disease

F Pistollato, SS Cano, I Elio, MM Vergara… - Advances in …, 2016 - Elsevier
Accumulation of proteinaceous amyloid β plaques and tau oligomers may occur several
years before the onset of Alzheimer disease (AD). Under normal circumstances, misfolded …

Depressive symptoms and cognitive decline: a longitudinal analysis of potentially modifiable risk factors in community dwelling older adults

D Gallagher, A Kiss, K Lanctot, N Herrmann - Journal of affective disorders, 2016 - Elsevier
Background Depressive symptoms have been associated with increased risk of cognitive
decline in later life. There are no interventions proven to reduce risk of cognitive decline in …

METACOHORTS for the study of vascular disease and its contribution to cognitive decline and neurodegeneration: An initiative of the Joint Programme for …

M Dichgans, J Wardlaw, E Smith, V Zietemann… - Alzheimer's & …, 2016 - Elsevier
Dementia is a global problem and major target for health care providers. Although up to 45%
of cases are primarily or partly due to cerebrovascular disease, little is known of these …

Nutrition and dementia: evidence for preventive approaches?

M Canevelli, F Lucchini, F Quarata, G Bruno, M Cesari - Nutrients, 2016 - mdpi.com
In recent years, the possibility of favorably influencing the cognitive trajectory through
promotion of lifestyle modifications has been increasingly investigated. In particular, the …

Frameworks for proof-of-concept clinical trials of interventions that target fundamental aging processes

J Justice, JD Miller, JC Newman… - … Series A: Biomedical …, 2016 - academic.oup.com
Therapies targeted at fundamental processes of aging may hold great promise for
enhancing the health of a wide population by delaying or preventing a range of age-related …

Interaction between cerebrovascular disease and Alzheimer pathology

S Saito, M Ihara - Current opinion in psychiatry, 2016 - journals.lww.com
Compared with Aβ pathology, little is known about the relationship between tau pathology
and CVD, although some studies have shown that CVD has an influence on tau pathology …

Emerging drugs to reduce abnormal β-amyloid protein in Alzheimer's disease patients

F Panza, D Seripa, V Solfrizzi, BP Imbimbo… - Expert Opinion on …, 2016 - Taylor & Francis
Introduction: Currently available drugs against Alzheimer's disease (AD) target cholinergic
and glutamatergic neurotransmissions without affecting the underlying disease process …

Dementias

SF Sacuiu - Handbook of clinical neurology, 2016 - Elsevier
This chapter will focus on the descriptive, analytic, and intervention-oriented epidemiology of
dementia and its most frequent etiologic type due to Alzheimer's disease. The chapter opens …

Three-year changes in leisure activities are associated with concurrent changes in white matter microstructure and perceptual speed in individuals aged 80 years and …

Y Köhncke, EJ Laukka, Y Brehmer, G Kalpouzos… - Neurobiology of …, 2016 - Elsevier
Accumulating evidence suggests that engagement in leisure activities is associated with
favorable trajectories of cognitive aging, but little is known about brain changes related to …

Allocation concealment in randomised controlled trials: are we getting better?

L Clark, C Fairhurst, DJ Torgerson - Bmj, 2016 - bmj.com
Allocation concealment in randomised controlled trials: are we getting better? Page 1 Allocation
concealment in randomised controlled trials: are we getting better? Laura Clark and colleagues …