Background: Engaging in late-life cognitive activity is often proposed as a strategy to delay
or prevent Alzheimer's disease (AD) and other dementias. However, it is unclear to what …

Objective—Cerebral vasoreactivity (CVR) is a key factor in maintenance of continuous
cerebral perfusion and a marker of (micro) vascular damage. We aimed to determine the …

Reducing cognitive decline in patients with Mild Cognitive Impairment (MCI) may slow their
progression to develop dementia. In this 12-week single-arm intervention trial, elderly …

Hypertension and dementia are two of the most prevalent and damaging diseases
associated with aging. Chronic hypertension, particularly during mid-life, is a strong risk …

This commentary outlines a conceptual model for subjective cognitive decline (SCD) in
relation to Alzheimer's disease (AD) biomarkers in the preclinical stages of disease and a …

Alzheimer's Disease: Lifecourse Perspectives on Risk Reduction summarizes the growing
body of knowledge on the distribution and causes of Alzheimer's disease (AD) in human …

Fighting against risk factors for disability and dependency throughout the whole life process
and–more specifically relevant to this paper–during the second part of life, needs to become …

Abstract Background Long before Alzheimer's disease was established as the leading
cause of dementia in old age, cerebrovascular lesions were known to cause cognitive …

Background: Nutrition among older people is associated with functional ability and quality of
life (QoL). Malnutrition is most often observed in institutionalized older people and …

Objective. To confirm that physical activity program improves the symptoms of dementia and
the most effective physical activity was selected to help establish exercise programs …