Genetic association of long-chain acyl-CoA synthetase 1 variants with fasting glucose, diabetes, and subclinical atherosclerosis [S]
Long-chain acyl-CoA synthetase 1 (ACSL1) converts free fatty acids into acyl-CoAs. Mouse
studies have revealed that ACSL1 channels acyl-CoAs to β-oxidation, thereby reducing …
studies have revealed that ACSL1 channels acyl-CoAs to β-oxidation, thereby reducing …
[图书][B] OMICS: biomedical perspectives and applications
D Barh, K Blum, MA Madigan - 2016 - books.google.com
A reflection of the explosion of research and development in this field, this book explores
applications of omics in bioinformatics, cancer research and therapy, diabetes research …
applications of omics in bioinformatics, cancer research and therapy, diabetes research …
Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice
Single nucleotide polymorphisms (SNPs) close to the VPS13C, C2CD4A and C2CD4B
genes on chromosome 15q are associated with impaired fasting glucose and increased risk …
genes on chromosome 15q are associated with impaired fasting glucose and increased risk …
Gene‐diet interaction of a common FADS1 variant with marine polyunsaturated fatty acids for fatty acid composition in plasma and erythrocytes among men
MJ Takkunen, VD de Mello, US Schwab… - Molecular nutrition & …, 2016 - Wiley Online Library
Scope Limited information exists on how the relationship between dietary intake of fat and
fatty acids in erythrocytes and plasma is modulated by polymorphisms in the FADS gene …
fatty acids in erythrocytes and plasma is modulated by polymorphisms in the FADS gene …
Peripheral blood transcriptomic signatures of fasting glucose and insulin concentrations
BH Chen, MF Hivert, MJ Peters, LC Pilling… - Diabetes, 2016 - Am Diabetes Assoc
Genome-wide association studies (GWAS) have successfully identified genetic loci
associated with glycemic traits. However, characterizing the functional significance of these …
associated with glycemic traits. However, characterizing the functional significance of these …
Genetic correlation analysis suggests association between increased self-reported sleep duration in adults and schizophrenia and type 2 diabetes
Abstract Study Objectives: We sought to examine how much of the heritability of self-report
sleep duration is tagged by common genetic variation in populations of European ancestry …
sleep duration is tagged by common genetic variation in populations of European ancestry …
Obesity and exercise-induced ectopic ventricular arrhythmias in apparently healthy middle aged adults
Background Obesity and overweight are strongly associated with cardiovascular morbidity
and mortality. However, there are limited data on the association between excess weight …
and mortality. However, there are limited data on the association between excess weight …
The mechanism of transactivation regulation due to polymorphic short tandem repeats (STRs) using IGF1 promoter as a model
Functional short tandem repeats (STR) are polymorphic in the population, and the number of
repeats regulates the expression of nearby genes (known as expression STR, eSTR). STR …
repeats regulates the expression of nearby genes (known as expression STR, eSTR). STR …
Assignment of functional relevance to genes at type 2 diabetes-associated loci through investigation of β-cell mass deficits
EA O'Hare, LM Yerges-Armstrong… - Molecular …, 2016 - academic.oup.com
Type 2 diabetes (T2D) has been associated with a large number of genomic loci, many of
which encompass multiple genes without a definitive causal gene. This complexity has …
which encompass multiple genes without a definitive causal gene. This complexity has …
Genetic component of type 2 diabetes in a Mexican population
K Sánchez-Pozos, M Menjivar - Archives of Medical Research, 2016 - Elsevier
Type 2 diabetes (T2D) is a complex disease caused by the interaction of genetic and
environmental factors. In this regard, it has been demonstrated that Hispanics have a greater …
environmental factors. In this regard, it has been demonstrated that Hispanics have a greater …