Genome‐wide association (GWA) meta‐analysis has become a popular approach for
discovering genetic variants responsible for complex diseases. The between‐study …

Aim We performed a replication study in a Japanese population to evaluate the association
between type 2 diabetes and six susceptibility loci (TMEM154, SSR1, FAF1, POU5F1 …

Background: Low-grade chronic inflammation is a common feature of obesity and its cardio-
metabolic complications. However, little is known about a possible causal role of …

Lower birthweight is consistently associated with a higher risk of type 2 diabetes in
observational studies, but the mechanisms underlying this association are not fully …

Although disproportionately affected by increasing rates of type 2 diabetes and
dyslipidemias, Hispanic populations are underrepresented in efforts to understand genetic …

Incretin effect enhancers are drugs used in the treatment of Type 2 diabetes and include
GLP-1 receptor agonists and dipeptidyl peptidase-4 inhibitors (gliptins). Variants in several …

Background—Cardiovascular risk factors tend to aggregate. The biological and predictive
value of this aggregation is questioned and genetics could shed light on this debate. Our …

Meta‐analysis of genome‐wide association studies (GWAS) has achieved great success in
detecting loci underlying human diseases. Incorporating GWAS results from diverse ethnic …

Background The future of medicine is moving towards the phase of precision medicine, with
the goal to prevent and treat diseases by taking inter-individual variability into account. A …

Type 2 diabetes (T2D) is the result of metabolic defects in insulin secretion and insulin
sensitivity, yet most T2D loci identified to date influence insulin secretion. We hypothesized …