Acute infectious gastroenteritis potentiates a Crohn's disease pathobiont to fuel ongoing inflammation in the post-infectious period
Crohn's disease (CD) is a chronic inflammatory condition of diverse etiology. Exposure to
foodborne pathogens causing acute gastroenteritis produces a long-term risk of CD well into …
foodborne pathogens causing acute gastroenteritis produces a long-term risk of CD well into …
Persistent infection with Crohn's disease-associated adherent-invasive Escherichia coli leads to chronic inflammation and intestinal fibrosis
CLN Small, SA Reid-Yu, JB McPhee… - Nature …, 2013 - nature.com
Crohn's disease is a chronic inflammatory condition of the gastrointestinal tract in which
alterations to the bacterial community contribute to disease. Adherent-invasive Escherichia …
alterations to the bacterial community contribute to disease. Adherent-invasive Escherichia …
[HTML][HTML] Subversion of human intestinal mucosa innate immunity by a Crohn's disease-associated E. coli
A Jarry, L Crémet, N Caroff, C Bou-Hanna… - Mucosal …, 2015 - Elsevier
Adherent-invasive Escherichia coli (AIEC), associated with Crohn's disease, are likely
candidate contributory factors in the disease. However, signaling pathways involved in …
candidate contributory factors in the disease. However, signaling pathways involved in …
The multifaceted virulence of adherent-invasive Escherichia coli
S Mansour, T Asrar, W Elhenawy - Gut Microbes, 2023 - Taylor & Francis
The surge in inflammatory bowel diseases, like Crohn's disease (CD), is alarming. While the
role of the gut microbiome in CD development is unresolved, the frequent isolation of …
role of the gut microbiome in CD development is unresolved, the frequent isolation of …
Understanding HostAdherentInvasive Escherichia coli Interaction in Crohn's Disease: Opening Up New Therapeutic Strategies
A Agus, S Massier, A Darfeuille-Michaud… - BioMed research …, 2014 - Wiley Online Library
A trillion of microorganisms colonize the mammalian intestine. Most of them have coevolved
with the host in a symbiotic relationship and some of them have developed strategies to …
with the host in a symbiotic relationship and some of them have developed strategies to …
Antibiotics Potentiate Adherent-Invasive E. coli Infection and Expansion
Background Crohn's disease (CD) is an inflammatory bowel disease with a complex
etiology. Paradoxically, CD is associated with the use of antibiotics and with an increased …
etiology. Paradoxically, CD is associated with the use of antibiotics and with an increased …
A polymicrobial view of disease potential in Crohn's-associated adherent-invasive E. coli
The human gut is home to trillions of bacteria and provides the scaffold for one of the most
complex microbial ecosystems in nature. Inflammatory bowel diseases, such as Crohn's …
complex microbial ecosystems in nature. Inflammatory bowel diseases, such as Crohn's …
An adherent-invasive Escherichia coli-colonized mouse model to evaluate microbiota-targeting strategies in Crohn's disease
A Sivignon, M Chervy, C Chevarin… - Disease Models & …, 2022 - journals.biologists.com
Adherent-invasive Escherichia coli (AIEC) were investigated for their involvement in the
induction/chronicity of intestinal inflammation in Crohn's disease (CD). AIEC gut …
induction/chronicity of intestinal inflammation in Crohn's disease (CD). AIEC gut …
Characterizing the pathogenic potential of Crohn's disease-associated adherent-invasive Escherichia coli
MT Zangara, L Darwish, BK Coombes - EcoSal Plus, 2023 - Am Soc Microbiol
The microbiome of Crohn's disease (CD) patients is composed of a microbial community that
is considered dysbiotic and proinflammatory in nature. The overrepresentation of …
is considered dysbiotic and proinflammatory in nature. The overrepresentation of …
Host-specific adaptive diversification of Crohn's disease-associated adherent-invasive Escherichia coli
Crohn's disease (CD) is an inflammatory bowel disease influenced by bacteria. Adherent-
invasive E. coli (AIEC) is associated with CD, yet the adaptations facilitating AIEC gut …
invasive E. coli (AIEC) is associated with CD, yet the adaptations facilitating AIEC gut …