Plasma levels of proprotein convertase subtilisin/kexin type 9 are elevated in patients with peripheral artery disease and associated with metabolic disorders and …

TH Chao, IC Chen, YH Li, PT Lee… - Journal of the American …, 2016 - Am Heart Assoc
Background Proprotein convertase subtilisin/kexin type 9 (PCSK 9) is involved in cholesterol
homeostasis, inflammation, and oxidative stress. This study investigated the association of …

Association of proprotein convertase subtilisin/kexin type 9 (PCSK9) with cardiovascular risk in primary prevention

YM Zhu, TJ Anderson, K Sikdar, M Fung… - … , and vascular biology, 2015 - Am Heart Assoc
Objective—Proprotein convertase subtilisin/kexin type 9 (PCSK9) plays an important role in
the modulation of low-density lipoprotein metabolism. This study was conducted to evaluate …

[HTML][HTML] Circulating levels of proprotein convertase subtilisin/kexin type 9 (PCSK9) are associated with monocyte subsets in patients with stable coronary artery …

KA Krychtiuk, M Lenz, P Hohensinner… - Journal of Clinical …, 2021 - Elsevier
Background Proprotein convertase subtilisin/kexin type-9 (PCSK9) is an enzyme promoting
the degradation of low-density lipoprotein receptors (LDL-R) in hepatocytes. Inhibition of …

Association of plasma PCSK9 levels with white blood cell count and its subsets in patients with stable coronary artery disease

S Li, YL Guo, RX Xu, Y Zhang, CG Zhu, J Sun, P Qing… - Atherosclerosis, 2014 - Elsevier
Objective Recent studies have suggested that proprotein convertase subtilisin/kexin type 9
(PCSK9) is associated with atherosclerosis and plays a potential role in inflammation …

Correlation between serum levels of proprotein convertase subtilisin/kexin type 9 (PCSK9) and atherogenic lipoproteins in patients with coronary artery disease

T Nozue, H Hattori, K Ogawa, T Kujiraoka… - Lipids in health and …, 2016 - Springer
Background Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a key regulator of
serum low-density lipoprotein (LDL) cholesterol levels. Recently, PCSK9 has additionally …

Plasma proprotein convertase subtilisin/kexin type 9 levels and the risk of first cardiovascular events

PM Ridker, N Rifai, G Bradwin, L Rose - European heart journal, 2016 - academic.oup.com
Aims Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a secreted protein that
enhances degradation of the LDL receptor. While agents that inhibit PCSK9 markedly …

The effect of proprotein convertase subtilisin kexin type 9 inhibitors on circulating endothelial progenitor cells in patients with cardiovascular disease

O Itzhaki Ben Zadok, A Mager, D Leshem-Lev… - … Drugs and Therapy, 2022 - Springer
Purpose Circulating endothelial progenitor cells (cEPCs) are vital to vascular repair by re-
endothelialization. We aimed to explore the effect of proprotein convertase subtilisin kexin …

Endogenous PCSK9 may influence circulating CD45neg/CD34bright and CD45neg/CD34bright/CD146neg cells in patients with type 2 diabetes mellitus

R Tripaldi, P Lanuti, PG Simeone, R Liani… - Scientific Reports, 2021 - nature.com
Protease proprotein convertase subtilisin/kexin type 9 (PCSK9) is a regulator of LDL
cholesterol clearance and has been associated with cardiovascular risk. PCSK9 inhibitors …

Circulating proprotein convertase subtilisin/kexin type 9 (PCSK9) predicts future risk of cardiovascular events independently of established risk factors

K Leander, A Mälarstig, FM van't Hooft, C Hyde… - Circulation, 2016 - Am Heart Assoc
Background—The secreted protein proprotein convertase subtilisin/kexin type 9 (PCSK9) is
a promising new target for lowering plasma low-density lipoprotein cholesterol and …

Serum Proprotein Convertase Subtilisin/Kexin type 9 and vascular disease in type 2 diabetic patients

G Armentaro, F Carbone, V Cassano… - European Journal of …, 2023 - Wiley Online Library
Abstract Background Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) levels have
been suggested as novel atherosclerotic biomarker. PCSK9 plays important roles in the …