The aberrant sialylation profile on the surface of leukemia cells has been recognized for its
potential diagnostic value towards assessing leukemia multidrug resistance (MDR) …

Cell surface sialylation is emerging as an important feature of cancer cell multidrug
resistance (MDR). We have focused on the influence of 2, 8‐sialyltransferases in key steps …

Acquired resistance to imatinib is frequently associated with poor clinical outcome of chronic
myeloid leukemia (CML) patient. To date, evidence indicates that protein glycosylation and …

Aberrant cell surface sialylation patterns have been shown to correlate with tumor
progression and metastasis. However, the role of sialylation regulation of cancer multidrug …

Chemotherapy resistance frequently drives tumor progression. Increased expression of
ST8SIA4 has been reported in diverse carcinomas and highly correlates with leukemia …

Abstract Background Noncoding RNAs, including microRNAs (miRNAs) and long non-
coding RNAs (lncRNAs) are becoming key parts in the development of multidrug resistance …

Background and aim The study examined sialylation changes for their potential predictive
value in assessment of imatinib mesylate (IM) resistance, alone and/or with BCR-ABL1 …

Polysialic acid (polySia), an α-2, 8-glycosidically linked polymer of sialic acid, is a
developmentally regulated post-translational modification predominantly found on NCAM …

β-galactoside α2, 6-sialyltransferse gene (ST6GAL) family has two members, which encode
corresponding enzymes ST6Gal I and ST6Gal II. The present atudy was to investigate …

Correlations of disease phenotypes with glycosylation changes have been analyzed
intensively in tumor biology field. In this study we describe glycomic alterations of multidrug …