Leishmaniasis is a neglected infection that is caused by Leishmania protozoa, affecting
millions of people worldwide, mainly in tropical and subtropical regions. This disease has …

Leishmaniasis, a complex of diseases caused by protozoa of the genus Leishmania, is
endemic in 98 countries, affecting approximately 12 million people worldwide. Current …

Background Human cutaneous leishmaniasis is caused by distinct species, including
Leishmania amazonensis. Treatment of cutaneous leishmaniasis is far from satisfactory due …

Leishmaniasis is a neglected tropical disease that affects millions of people worldwide.
Current therapies mainly rely on antimonial drugs that are inadequate because of their high …

Leishmaniasis are a neglected group of emerging diseases that have been found in 98
countries and are caused by protozoa of the genus Leishmania. The therapy for …

Background: Three drugs-pentavalent antimonials, amphotericin B and pentamidine-are
currently used for leishmaniasis treatment. They are administered for long periods, only …

Since the discovery of the28 first drugs used in leishmaniasis treatment up to now, the
search for compounds with anti-Leishmania activity without toxic effects and able to …

Leishmaniasis is a disease that affects millions of people worldwide. The drugs that are
available for the treatment of this infection exhibit high toxicity and various side effects …

This study was performed to investigate the mechanistic aspects of cell death induced by a
clerodane diterpene (K-09) in Leishmania donovani promastigotes that was previously …

Background Leishmania amazonensis infection results in diverse clinical manifestations:
cutaneous, mucocutaneous or visceral leishmaniasis. The arsenal of drugs available for …