Identifying N-Glycan Biomarkers in Colorectal Cancer by Mass Spectrometry
MK Sethi, WS Hancock, S Fanayan - Accounts of chemical …, 2016 - ACS Publications
Conspectus Colorectal cancer (CRC) is one of the most prevalent cancers worldwide.
Delineating biological markers (biomarkers) for early detection, when treatment is most …
Delineating biological markers (biomarkers) for early detection, when treatment is most …
[HTML][HTML] Profound diversity of the N-glycome from microdissected regions of colorectal cancer, stroma, and normal colon mucosa
Aberrant glycosylation is considered to be a hallmark of colorectal cancer (CRC), as
demonstrated by various studies. While the N-glycosylation of cell lines and serum has been …
demonstrated by various studies. While the N-glycosylation of cell lines and serum has been …
In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation
Glycomics may assist in uncovering the structure–function relationships of protein
glycosylation and identify glycoprotein markers in colorectal cancer (CRC) research. Herein …
glycosylation and identify glycoprotein markers in colorectal cancer (CRC) research. Herein …
[HTML][HTML] N-glycomic profiling of colorectal cancer according to tumor stage and location
M Holm, P Nummela, A Heiskanen, T Satomaa… - PLoS …, 2020 - journals.plos.org
Alterations in glycosylation are seen in many types of cancer, including colorectal cancer
(CRC). Glycans, the sugar moieties of glycoconjugates, are involved in many important …
(CRC). Glycans, the sugar moieties of glycoconjugates, are involved in many important …
[HTML][HTML] N-glycomic profiling as a tool to separate rectal adenomas from carcinomas
All human cells are covered by glycans, the carbohydrate units of glycoproteins, glycolipids,
and proteoglycans. Most glycans are localized to cell surfaces and participate in events …
and proteoglycans. Most glycans are localized to cell surfaces and participate in events …
[HTML][HTML] N-glycosylation of colorectal cancer tissues: a liquid chromatography and mass spectrometry-based investigation
CIA Balog, K Stavenhagen, WLJ Fung… - Molecular & Cellular …, 2012 - ASBMB
Colorectal cancer is the third most common cancer worldwide with an annual incidence of∼
1 million cases and an annual mortality rate of∼ 655,000 individuals. There is an urgent …
1 million cases and an annual mortality rate of∼ 655,000 individuals. There is an urgent …
[HTML][HTML] Mass Spectrometry-Based N-Glycomics of Colorectal Cancer
MK Sethi, S Fanayan - International journal of molecular sciences, 2015 - mdpi.com
Colorectal cancer (CRC) is one of the most prevalent cancers worldwide. An increased
molecular understanding of the CRC pathology is warranted to gain insights into the …
molecular understanding of the CRC pathology is warranted to gain insights into the …
[HTML][HTML] Identification of differential N-glycan compositions in the serum and tissue of colon cancer patients by mass spectrometry
MMA Coura, EA Barbosa, GD Brand, C Bloch Jr… - Biology, 2021 - mdpi.com
Simple Summary Incidence of colorectal cancer (CRC) has been rising in Brazil. To date, no
reliable biomarker has been described in CRC for diagnosis and prognosis. Modifications in …
reliable biomarker has been described in CRC for diagnosis and prognosis. Modifications in …
[HTML][HTML] High-Mannose N-Glycans as Malignant Progression Markers in Early-Stage Colorectal Cancer
F Boyaval, H Dalebout, R Van Zeijl, W Wang… - Cancers, 2022 - mdpi.com
Simple Summary The detection of colorectal cancer (CRC) at an early stage is increasing
due to the implementation of screening programs. Local excision of early CRC is potentially …
due to the implementation of screening programs. Local excision of early CRC is potentially …
[HTML][HTML] Trends in oligomannosylation and α1, 2-mannosidase expression in human cancers
S Chatterjee, J Ugonotti, LY Lee, A Everest-Dass… - Oncotarget, 2021 - ncbi.nlm.nih.gov
Aberrant protein glycosylation is a prominent cancer feature. While many tumour-associated
glycoepitopes have been reported, advances in glycoanalytics continue to uncover new …
glycoepitopes have been reported, advances in glycoanalytics continue to uncover new …