Cerenkov luminescence imaging (CLI) for image-guided cancer surgery

MR Grootendorst, M Cariati, A Kothari, DS Tuch… - Clinical and translational …, 2016 - Springer
Cerenkov luminescence imaging (CLI) is a novel molecular optical imaging technique
based on the detection of optical Cerenkov photons emitted by positron emission …

Intraoperative imaging of tumors using Cerenkov luminescence endoscopy: a feasibility experimental study

H Liu, CM Carpenter, H Jiang, G Pratx… - Journal of Nuclear …, 2012 - Soc Nuclear Med
Cerenkov luminescence imaging (CLI) is an emerging new molecular imaging modality that
is relatively inexpensive, easy to use, and has high throughput. CLI can image clinically …

A novel endoscopic Cerenkov luminescence imaging system for intraoperative surgical navigation

T Song, X Liu, Y Qu, H Liu, C Bao, C Leng… - Molecular …, 2015 - journals.sagepub.com
Cerenkov luminescence imaging is an emerging optical technique for imaging the
distribution of radiopharmaceuticals in vivo. However, because of the light scattering effect, it …

Cerenkov imaging

S Das, DLJ Thorek, J Grimm - Advances in cancer research, 2014 - Elsevier
Cerenkov luminescence (CL) has been used recently in a plethora of medical applications
like imaging and therapy with clinically relevant medical isotopes. The range of medical …

Intraoperative imaging of positron emission tomographic radiotracers using Cerenkov luminescence emissions

JP Holland, G Normand, A Ruggiero… - Molecular …, 2011 - journals.sagepub.com
Imaging the location and extent of cancer provides invaluable information before, during,
and after surgery. The majority of “image-guided” methods that use, for example, positron …

Prospective testing of clinical Cerenkov luminescence imaging against standard-of-care nuclear imaging for tumour location

EC Pratt, M Skubal, B Mc Larney… - Nature biomedical …, 2022 - nature.com
In oncology, the feasibility of Cerenkov luminescence imaging (CLI) has been assessed by
imaging superficial lymph nodes in a few patients undergoing diagnostic 18F-fluoro-2 …

Optical imaging as an expansion of nuclear medicine: Cerenkov-based luminescence vs fluorescence-based luminescence

PTK Chin, MM Welling, SCJ Meskers… - European journal of …, 2013 - Springer
Integration of optical imaging technologies can further strengthen the field of radioguided
surgery. Rather than using two separate chemical entities to achieve this extension, hybrid …

Endoscopic imaging of Cerenkov luminescence

SR Kothapalli, H Liu, JC Liao, Z Cheng… - Biomedical optics …, 2012 - opg.optica.org
We demonstrate feasibility of endoscopic imaging of Cerenkov light originated when
charged nuclear particles, emitted from radionuclides, travel through a biological tissue of …

Endoscopic Cerenkov luminescence imaging and image-guided tumor resection on hepatocellular carcinoma-bearing mouse models

Z Zhang, M Cai, C Bao, Z Hu, J Tian - … : Nanotechnology, Biology and …, 2019 - Elsevier
Detecting deep tumors inside living subject is still challenging for Cerenkov luminescence
imaging (CLI). In this study, a high-sensitivity endoscopic CLI (ECLI) system was developed …

Innovations in nuclear imaging instrumentation: Cerenkov imaging

R Tamura, EC Pratt, J Grimm - Seminars in nuclear medicine, 2018 - Elsevier
Cerenkov luminescence (CL) is blue glow light produced by charged subatomic particles
travelling faster than the phase velocity of light in a dielectric medium such as water or …