Traumatic brain injury-induced autoregulatory dysfunction and spreading depression-related neurovascular uncoupling: Pathomechanisms, perspectives, and …

P Toth, N Szarka, E Farkas, E Ezer… - American Journal …, 2016 - journals.physiology.org
Traumatic brain injury (TBI) is a major health problem worldwide. In addition to its high
mortality (35–40%), survivors are left with cognitive, behavioral, and communicative …

[HTML][HTML] Role of microvascular disruption in brain damage from traumatic brain injury

AF Logsdon, BP Lucke-Wold, RC Turner… - Comprehensive …, 2015 - ncbi.nlm.nih.gov
Traumatic brain injury (TBI) is acquired from an external force, which can inflict devastating
effects to the brain vasculature and neighboring neuronal cells. Disruption of vasculature is …

Spreading depression and neurovascular coupling

C Ayata - Stroke, 2013 - Am Heart Assoc
S88 Stroke June 2013 or injury depolarizations. 19, 20 Interestingly, the vasoconstrictive
components are most conspicuous during the first spreading depression in naïve tissue, and …

Chronic cerebrovascular dysfunction after traumatic brain injury

A Jullienne, A Obenaus, A Ichkova… - Journal of …, 2016 - Wiley Online Library
Traumatic brain injuries (TBI) often involve vascular dysfunction that leads to long‐term
alterations in physiological and cognitive functions of the brain. Indeed, all the cells that form …

Traumatic Brain Injury Impairs Myogenic Constriction of Cerebral Arteries: Role of Mitochondria-Derived H2O2 and TRPV4-Dependent Activation of BKca Channels

N Szarka, MR Pabbidi, K Amrein, E Czeiter… - Journal of …, 2018 - liebertpub.com
Traumatic brain injury (TBI) impairs autoregulation of cerebral blood flow, which contributes
to the development of secondary brain injury, increasing mortality of patients. Impairment of …

[HTML][HTML] Cerebrovascular dysfunction with stress and depression

E Burrage, KL Marshall, N Santanam… - Brain …, 2018 - journals.lww.com
Maintenance of adequate tissue perfusion through a dense network of cerebral
microvessels is critical for the perseveration of normal brain function. Regulation of the …

Excitation-inhibition imbalance leads to alteration of neuronal coherence and neurovascular coupling under acute stress

K Han, M Lee, HK Lim, MW Jang, J Kwon… - Journal of …, 2020 - Soc Neuroscience
A single stressful event can cause morphologic and functional changes in neurons and even
malfunction of vascular systems, which can lead to acute stress disorder or post-traumatic …

Neural vascular mechanism for the cerebral blood flow autoregulation after hemorrhagic stroke

M Xiao, Q Li, H Feng, L Zhang, Y Chen - Neural plasticity, 2017 - Wiley Online Library
During the initial stages of hemorrhagic stroke, including intracerebral hemorrhage and
subarachnoid hemorrhage, the reflex mechanisms are activated to protect cerebral …

Response of the cerebral vasculature following traumatic brain injury

A Salehi, JH Zhang, A Obenaus - Journal of Cerebral Blood …, 2017 - journals.sagepub.com
The critical role of the vasculature and its repair in neurological disease states is beginning
to emerge particularly for stroke, dementia, epilepsy, Parkinson's disease, tumors and …

[HTML][HTML] Cerebrovascular reactivity is not associated with therapeutic intensity in adult traumatic brain injury: a CENTER-TBI analysis

FA Zeiler, A Ercole, E Beqiri, M Cabeleira, M Aries… - Acta …, 2019 - Springer
Background Impaired cerebrovascular reactivity in adult traumatic brain injury (TBI) is known
to be associated with poor outcome. However, there has yet to be an analysis of the …