Traumatic brain injury-induced autoregulatory dysfunction and spreading depression-related neurovascular uncoupling: Pathomechanisms, perspectives, and …
Traumatic brain injury (TBI) is a major health problem worldwide. In addition to its high
mortality (35–40%), survivors are left with cognitive, behavioral, and communicative …
mortality (35–40%), survivors are left with cognitive, behavioral, and communicative …
[HTML][HTML] Role of microvascular disruption in brain damage from traumatic brain injury
AF Logsdon, BP Lucke-Wold, RC Turner… - Comprehensive …, 2015 - ncbi.nlm.nih.gov
Traumatic brain injury (TBI) is acquired from an external force, which can inflict devastating
effects to the brain vasculature and neighboring neuronal cells. Disruption of vasculature is …
effects to the brain vasculature and neighboring neuronal cells. Disruption of vasculature is …
Spreading depression and neurovascular coupling
C Ayata - Stroke, 2013 - Am Heart Assoc
S88 Stroke June 2013 or injury depolarizations. 19, 20 Interestingly, the vasoconstrictive
components are most conspicuous during the first spreading depression in naïve tissue, and …
components are most conspicuous during the first spreading depression in naïve tissue, and …
Chronic cerebrovascular dysfunction after traumatic brain injury
A Jullienne, A Obenaus, A Ichkova… - Journal of …, 2016 - Wiley Online Library
Traumatic brain injuries (TBI) often involve vascular dysfunction that leads to long‐term
alterations in physiological and cognitive functions of the brain. Indeed, all the cells that form …
alterations in physiological and cognitive functions of the brain. Indeed, all the cells that form …
Traumatic Brain Injury Impairs Myogenic Constriction of Cerebral Arteries: Role of Mitochondria-Derived H2O2 and TRPV4-Dependent Activation of BKca Channels
Traumatic brain injury (TBI) impairs autoregulation of cerebral blood flow, which contributes
to the development of secondary brain injury, increasing mortality of patients. Impairment of …
to the development of secondary brain injury, increasing mortality of patients. Impairment of …
[HTML][HTML] Cerebrovascular dysfunction with stress and depression
E Burrage, KL Marshall, N Santanam… - Brain …, 2018 - journals.lww.com
Maintenance of adequate tissue perfusion through a dense network of cerebral
microvessels is critical for the perseveration of normal brain function. Regulation of the …
microvessels is critical for the perseveration of normal brain function. Regulation of the …
Excitation-inhibition imbalance leads to alteration of neuronal coherence and neurovascular coupling under acute stress
A single stressful event can cause morphologic and functional changes in neurons and even
malfunction of vascular systems, which can lead to acute stress disorder or post-traumatic …
malfunction of vascular systems, which can lead to acute stress disorder or post-traumatic …
Neural vascular mechanism for the cerebral blood flow autoregulation after hemorrhagic stroke
During the initial stages of hemorrhagic stroke, including intracerebral hemorrhage and
subarachnoid hemorrhage, the reflex mechanisms are activated to protect cerebral …
subarachnoid hemorrhage, the reflex mechanisms are activated to protect cerebral …
Response of the cerebral vasculature following traumatic brain injury
The critical role of the vasculature and its repair in neurological disease states is beginning
to emerge particularly for stroke, dementia, epilepsy, Parkinson's disease, tumors and …
to emerge particularly for stroke, dementia, epilepsy, Parkinson's disease, tumors and …
[HTML][HTML] Cerebrovascular reactivity is not associated with therapeutic intensity in adult traumatic brain injury: a CENTER-TBI analysis
Background Impaired cerebrovascular reactivity in adult traumatic brain injury (TBI) is known
to be associated with poor outcome. However, there has yet to be an analysis of the …
to be associated with poor outcome. However, there has yet to be an analysis of the …
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