Inflammation and the microbiome: implications for depressive disorders

S Hayley, MC Audet, H Anisman - Current opinion in pharmacology, 2016 - Elsevier
Highlights•Activation of the inflammatory immune system may contribute to depressive
disorders.•Disturbed balance between varied gut bacteria could activate inflammatory …

Gut microbiota–brain axis in depression: The role of neuroinflammation

AS Carlessi, LA Borba, AI Zugno… - European Journal of …, 2021 - Wiley Online Library
Major depressive disorder (MDD) is a psychiatric condition that affects a large number of
people in the world, and the treatment existents do not work for all individuals affected. Thus …

[HTML][HTML] Beyond the neuro-immune interplay in depression: Could gut microbes be the missing link?

MC Audet - Brain, Behavior, & Immunity-Health, 2021 - Elsevier
Accumulating evidence have positioned inflammatory signaling pathways as crucial routes
by which microbes inhabiting the gastrointestinal tract (the gut microbiota) communicate with …

Stress, inflammation, microbiome and depression

EM Medina-Rodriguez, AA Cruz, JC De Abreu… - Pharmacology …, 2023 - Elsevier
Psychiatric disorders are mental illnesses involving changes in mood, cognition and
behavior. Their prevalence has rapidly increased in the last decades. One of the most …

Nutraceuticals and Physical Activity as Antidepressants: The Central Role of the Gut Microbiota

S Donati Zeppa, F Ferrini, D Agostini, S Amatori… - Antioxidants, 2022 - mdpi.com
Major depressive disorder (MDD) is a common mental illness. Evidence suggests that the
gut microbiota play an essential role in regulating brain functions and the pathogenesis of …

Gut microbiota in mental health and depression: Role of pre/pro/synbiotics in their modulation

HN Methiwala, B Vaidya, VK Addanki, M Bishnoi… - Food & Function, 2021 - pubs.rsc.org
The microbiome residing in the human gut performs a wide range of biological functions.
Recently, it has been elucidated that a change in dietary habits is associated with alteration …

Depressed gut? The microbiota-diet-inflammation trialogue in depression

M Koopman, S El Aidy - Current opinion in psychiatry, 2017 - journals.lww.com
The review summarizes the existent literature on this emerging research field and provides a
comprehensive overview of the multifaceted links between the microbiota, diet, and …

Depression's unholy trinity: dysregulated stress, immunity, and the microbiome

JS Cruz-Pereira, K Rea, YM Nolan… - Annual review of …, 2020 - annualreviews.org
Depression remains one of the most prevalent psychiatric disorders, with many patients not
responding adequately to available treatments. Chronic or early-life stress is one of the key …

Role of the intestinal microbiome, intestinal barrier and psychobiotics in depression

P Trzeciak, M Herbet - Nutrients, 2021 - mdpi.com
The intestinal microbiota plays an important role in the pathophysiology of depression. As
determined, the microbiota influences the shaping and modulation of the functioning of the …

[HTML][HTML] Gut microbiota and pathophysiology of depressive disorder

H Kunugi - Annals of Nutrition and Metabolism, 2021 - karger.com
Background: Accumulating evidence has suggested that the bi-directional communication
pathway, the microbiota-gut-brain axis, plays an important role in the pathophysiology of …