Transurethral instillation with fusion protein MrpH.FimH induces protective innate immune responses against uropathogenic Escherichia coli and Proteus mirabilis

M Habibi, MR Asadi Karam, S Bouzari - Apmis, 2016 - Wiley Online Library
Urinary tract infections (UTI s) are among the most common infections in human. Innate
immunity recognizes pathogen‐associated molecular patterns (PAMP s) by Toll‐like …

Intranasal immunization with fusion protein MrpH· FimH and MPL adjuvant confers protection against urinary tract infections caused by uropathogenic Escherichia coli …

M Habibi, MRA Karam, MA Shokrgozar, M Oloomi… - Molecular …, 2015 - Elsevier
Urinary tract infections (UTIs) caused by Uropathogenic Escherichia coli (UPEC) and
Proteus mirabilis are among the most common infections in the world. Currently there are no …

Vaccination with recombinant FimH fused with flagellin enhances cellular and humoral immunity against urinary tract infection in mice

MRA Karam, M Oloomi, M Mahdavi, M Habibi… - Vaccine, 2013 - Elsevier
Urinary tract infection (UTI) caused by Uropathogenic Escherichia coli (UPEC) is one of the
most common infections in the world. Despite extensive efforts, a vaccine that confers …

Determination immunogenic property of truncated MrpH. FliC as a vaccine candidate against urinary tract infections caused by Proteus mirabilis

Z Bameri, MRA Karam, M Habibi, P Ehsani… - Microbial …, 2018 - Elsevier
Proteus mirabilis is common cause of urinary tract infections (UTIs) especially in complicated
UTIs which are resistant to antibiotic therapy, Consequently, an ideal vaccine is inevitably …

Evaluation of the effect of MPL and delivery route on immunogenicity and protectivity of different formulations of FimH and MrpH from uropathogenic Escherichia coli …

M Habibi, MRA Karam, S Bouzari - International Immunopharmacology, 2015 - Elsevier
Urinary tract infections (UTIs) caused by Escherichia coli and Proteus mirabilis are an
important cause of morbidity and with the high rate of relapse and spread of multi-drug …

Construction and evaluation of the immune protection of a recombinant divalent protein composed of the MrpA from MR/P fimbriae and flagellin of Proteus mirabilis …

M Habibi, MRA Karam, S Bouzari - Microbial pathogenesis, 2018 - Elsevier
Urinary tract infections (UTI) caused by Proteus mirabilis are prevalent among the
catheterized patients. There is no effective vaccine to reduce the frequency of UTIs caused …

[HTML][HTML] In silico design of fusion protein of FimH from uropathogenic Escherichia coli and MrpH from Proteus mirabilis against urinary tract infections

M Habibi, MRA Karam, S Bouzari - Advanced biomedical research, 2015 - journals.lww.com
Background: Urinary tract infections (UTIs) caused by uropathogenic Escherichia coli
(UPEC) and Proteus mirabilis are the most important pathogens causing UTIs. The FimH …

Assessment of immune responses of the flagellin (FliC) fused to FimH adhesin of Uropathogenic Escherichia coli

MRA Karam, M Oloomi, M Mahdavi, M Habibi… - Molecular …, 2013 - Elsevier
Urinary tract infection (UTI) caused by Uropathogenic Escherichia coli (UPEC) is one of the
most common infectious diseases in the world. Despite extensive efforts, a vaccine that …

[HTML][HTML] Protective multi-epitope candidate vaccine for urinary tract infection

M Oloomi, M Javadi, MRA Karam, JK Khezerloo… - Biotechnology …, 2020 - Elsevier
Urinary tract infections (UTIs) are induced by exogenous organisms including extraintestinal
pathogenic such as Escherichia coli (ExPEC), Proteus mirabilis and Klebsiella pneumonia …

[HTML][HTML] Cellular immunity survey against urinary tract infection using pVAX/fimH cassette with mammalian and wild type codon usage as a DNA vaccine

AAI Fooladi, G Bagherpour… - Clinical and …, 2014 - synapse.koreamed.org
Purpose FimH (the adhesion fragment of type 1 fimbriae) is implicated in uropathogenic
Escherichia coli (UPEC) attachment to epithelial cells through interaction with mannose …