Craniosynostosis: current conceptions and misconceptions

CSR Fonteles, RH Finnell, TM George… - Aims …, 2016 - thieme-connect.com
Cranial bones articulate in areas called sutures that must remain patent until skull growth is
complete. Craniosynostosis is the condition that results from premature closure of one or …

Understanding craniosynostosis as a growth disorder

K Flaherty, N Singh… - Wiley Interdisciplinary …, 2016 - Wiley Online Library
Craniosynostosis is a condition of complex etiology that always involves the premature
fusion of one or multiple cranial sutures and includes various anomalies of the soft and hard …

[HTML][HTML] Signaling mechanisms underlying genetic pathophysiology of craniosynostosis

X Wu, Y Gu - International journal of biological sciences, 2019 - ncbi.nlm.nih.gov
Craniosynostosis, is the premature fusion of one or more cranial sutures which is the second
most common cranial facial anomalies. The premature cranial sutures leads to deformity of …

Cranial suture biology: from pathways to patient care

B Levi, DC Wan, VW Wong, E Nelson… - Journal of …, 2012 - journals.lww.com
Craniosynostosis describes the premature pathologic partial or complete fusion of 1 or more
of the cranial sutures. Over the past few decades, research on craniosynostosis has …

The clinical manifestations, molecular mechanisms and treatment of craniosynostosis

E Stanton, M Urata, JF Chen… - Disease Models & …, 2022 - journals.biologists.com
Craniosynostosis is a major congenital craniofacial disorder characterized by the premature
fusion of cranial suture (s). Patients with severe craniosynostosis often have impairments in …

[HTML][HTML] Signaling mechanisms implicated in cranial sutures pathophysiology: Craniosynostosis

MA Katsianou, C Adamopoulos, H Vastardis… - BBA clinical, 2016 - Elsevier
Normal extension and skull expansion is a synchronized process that prevails along the
osteogenic intersections of the cranial sutures. Cranial sutures operate as bone growth sites …

Signal transduction pathways and their impairment in syndromic craniosynostosis

JJ Connerney, DB Spicer - Craniosynostoses, 2011 - karger.com
The cranial sutures act as the growth centers for the flat bones of the skull. They regulate the
growth of these bones, but also prevent their premature fusion, known as craniosynostosis …

Recent advances in craniosynostosis

E Yilmaz, E Mihci, B Nur, ÖM Alper, Ş Taçoy - Pediatric Neurology, 2019 - Elsevier
Craniosynostosis is a pathologic craniofacial disorder and is defined as the premature
fusion of one or more cranial (calvarial) sutures. Cranial sutures are fibrous joints consisting …

Current treatment of craniosynostosis and future therapeutic directions

DC Wan, MD Kwan, HP Lorenz, MT Longaker - Craniofacial Sutures, 2008 - karger.com
Normal craniofacial development is contingent upon coordinated growth between the brain
and overlying calvaria. Craniosynostosis, the premature fusion of one or more cranial …

Cranial sutures: a brief review

BJ Slater, KA Lenton, MD Kwan… - Plastic and …, 2008 - journals.lww.com
Craniosynostosis, or the premature fusion of one or more cranial sutures, is a relatively
common congenital defect that causes a number of morphologic and functional …