Divergent polo box domains underpin the unique kinetoplastid kinetochore
OO Nerusheva, B Akiyoshi - Open biology, 2016 - royalsocietypublishing.org
Kinetochores are macromolecular machines that drive eukaryotic chromosome segregation
by interacting with centromeric DNA and spindle microtubules. While most eukaryotes …
by interacting with centromeric DNA and spindle microtubules. While most eukaryotes …
Divergent polo boxes in KKT2 bind KKT1 to initiate the kinetochore assembly cascade in Trypanosoma brucei
M Ishii, P Ludzia, G Marcianò, W Allen… - Molecular Biology of …, 2022 - Am Soc Cell Biol
Chromosome segregation requires assembly of the macromolecular kinetochore complex
onto centromeric DNA. While most eukaryotes have canonical kinetochore proteins that are …
onto centromeric DNA. While most eukaryotes have canonical kinetochore proteins that are …
Kinetoplastid kinetochore proteins KKT2 and KKT3 have unique centromere localization domains
G Marciano, M Ishii, OO Nerusheva, B Akiyoshi - Journal of Cell Biology, 2021 - rupress.org
The kinetochore is the macromolecular protein complex that assembles onto centromeric
DNA and binds spindle microtubules. Evolutionarily divergent kinetoplastids have an …
DNA and binds spindle microtubules. Evolutionarily divergent kinetoplastids have an …
Identification of four unconventional kinetoplastid kinetochore proteins KKT22–25 in Trypanosoma brucei
OO Nerusheva, P Ludzia, B Akiyoshi - Open biology, 2019 - royalsocietypublishing.org
The kinetochore is a multi-protein complex that drives chromosome segregation in
eukaryotes. It assembles onto centromere DNA and interacts with spindle microtubules …
eukaryotes. It assembles onto centromere DNA and interacts with spindle microtubules …
[HTML][HTML] Discovery of unconventional kinetochores in kinetoplastids
B Akiyoshi, K Gull - Cell, 2014 - cell.com
The kinetochore is the macromolecular protein complex that directs chromosome
segregation in eukaryotes. It has been widely assumed that the core kinetochore consists of …
segregation in eukaryotes. It has been widely assumed that the core kinetochore consists of …
Characterization of unconventional kinetochore kinases KKT10 and KKT19 in Trypanosoma brucei
M Ishii, B Akiyoshi - Journal of cell science, 2020 - journals.biologists.com
The kinetochore is a macromolecular protein complex that drives chromosome segregation
in eukaryotes. Unlike most eukaryotes that have canonical kinetochore proteins …
in eukaryotes. Unlike most eukaryotes that have canonical kinetochore proteins …
Ndc80/Nuf2-like protein KKIP1 connects a stable kinetoplastid outer kinetochore complex to the inner kinetochore and responds to metaphase tension
L Brusini, S D'Archivio, J McDonald, B Wickstead - BioRxiv, 2019 - biorxiv.org
Kinetochores perform an essential role in eukaryotes, coupling chromosomes to the mitotic
spindle. In model organisms they are composed of a centromere-proximal inner kinetochore …
spindle. In model organisms they are composed of a centromere-proximal inner kinetochore …
[HTML][HTML] Trypanosome KKIP1 dynamically links the inner kinetochore to a kinetoplastid outer kinetochore complex
L Brusini, S D'Archivio, J McDonald… - Frontiers in cellular and …, 2021 - frontiersin.org
Kinetochores perform an essential role in eukaryotes, coupling chromosomes to the mitotic
spindle. In model organisms they are composed of a centromere-proximal inner kinetochore …
spindle. In model organisms they are composed of a centromere-proximal inner kinetochore …
Trypanosome outer kinetochore proteins suggest conservation of chromosome segregation machinery across eukaryotes
S D'Archivio, B Wickstead - Journal of Cell Biology, 2017 - rupress.org
Kinetochores are multiprotein complexes that couple eukaryotic chromosomes to the mitotic
spindle to ensure proper segregation. The model for kinetochore assembly is conserved …
spindle to ensure proper segregation. The model for kinetochore assembly is conserved …
A CLK1-KKT2 signaling pathway regulating kinetochore assembly in Trypanosoma brucei
M Saldivia, AJM Wollman, JBT Carnielli, NG Jones… - MBio, 2021 - Am Soc Microbiol
During mitosis, eukaryotic cells must duplicate and separate their chromosomes in a precise
and timely manner. The apparatus responsible for this is the kinetochore, which is a large …
and timely manner. The apparatus responsible for this is the kinetochore, which is a large …