Aberrant glycosylation in tumours stem from altered glycosyltransferase (GT) gene
expression but can the expression profiles of these signature genes be used to classify …

Simple Summary Cancer-associated glycosylation changes are widely used as biomarkers
and strongly impact malignancy. However, the clinical significance of the deranged …

Alterations in glycan structures are early signs of malignancy and have recently been
proposed to be in part a driving force behind malignant transformation. Here, we explore …

Glycosylation is a well-regulated cell and microenvironment specific post-translational
modification. Several glycosyltransferases and glycosidases orchestrate the addition of …

Tumor glycolysis is a major promoter of carcinogenesis and cancer progression. Given its
complex mechanisms and interactions, comprehensive analysis is needed to reveal its …

Glycosylation is among the most important post-translational modifications for proteins and
is of intrinsic complex character compared with DNAs and naked proteins. Indeed, over 50 …

Objective The abnormal expression of the key enzymes in glycolytic pathways, including
glucose transporter-1, glucose transporter-3, hexokinase-II, lactate dehydrogenase 5 …

Glycosylation of cellular proteins has important impact on their stability and functional
properties, and glycan structures strongly influence cell adhesion. Many enzymes are …

The molecular basis of aberrant protein glycosylation, a pathological alteration widespread
in colorectal cancers (CRC) and the mechanisms by which it contributes to tumor …

The change of cellular glycosylation is one of the key events in malignant transformation and
neoplastic progression, and tumor‐related glycosylation alterations are promising targets in …