Aortic dissection (AD) is a life-threatening aortopathy with high mortality. To mimic
spontaneous AD, investigate the pathogenesis of AD and develop novel therapeutic targets …

Thoracic aortic dissection (TAD) is one of the most lethal aortic diseases due to its acute
onset, rapid progress, and high rate of aortic rupture. The pathogenesis of TAD is not …

Aortic dissection (AD) is a potentially fatal cardiovascular emergency caused by separation
of different layers of aortic wall. However, because of limited time window available for …

Background Stanford type B dissection of the descending aorta is a potentially fatal
condition that is poorly understood. Limited scientific understanding of the role of current …

Aortic dissection (AD) is a serious clinical condition that is unpredictable and frequently
results in fatal outcome. Although rapamycin, an inhibitor of mechanistic target of rapamycin …

Aortic dissection (AD) has an unfavorable prognosis. It requires early diagnosis, appropriate
treatment strategies, and suspicion to recognize symptoms; thus, it is commonly described …

Objective: Aortic dissection is a life-threatening disease. At present, the only therapeutic
strategies available are surgery and antihypertensive drugs. Moreover, the molecular …

Aortic dissection confers high mortality and morbidity rates despite advances in treatment,
impacts quality of life, and contributes immense burden to the healthcare system globally …

Aortic dissection is an age-dependent life-threatening cardiovascular disease with high
mortality rates. Recent research has shown that inflammation plays an important role in …

Aortic dissection, occurring following a separation of the layers constituting the complex
vascular walls, leads to the formation of a 'false'lumen and disrupts the regulation of aortic …