In general, human muscular dystrophies are caused by mutations in genes encoding for key
proteins of the muscular tissue. A specific group of muscular dystrophies is related to …

Congenital muscular dystrophies (CMDs) are inherited, progressive and heterogeneous
muscle disorders. A group of CMDs are dystroglycanopathies, also called α …

Dystroglycan is a major non‐integrin adhesion complex that connects the cytoskeleton to the
surrounding basement membranes, thus providing stability to skeletal muscle. In …

The dystroglycanopathies are a group of inherited muscular dystrophies that have a
common underlying mechanism, hypoglycosylation of the extracellular receptor α …

A common group of muscular dystrophies is associated with the aberrant glycosylation of α-
dystroglycan. These clinically heterogeneous disorders, collectively termed …

Dystroglycanopathy is a collective term referring to muscular dystrophies with abnormal
glycosylation of dystroglycan. At least 18 causative genes of dystroglycanopathy have been …

Dystroglycan is a transmembrane protein that connects the extracellular matrix to the
cytoskeleton. Given the ubiquitous tissue expression of dystroglycan, different functional …

An increasing number of congenital muscular dystrophies might originate from genetic
abnormalities of glycosyltransferases genes which are believed to target the α subunit of the …

Dystroglycanopathies are neuromuscular disorders due to abnormal glycosylation of
dystroglycan which is a cell-surface glycoprotein that acts as a receptor for extracellular …

Abstract α-Dystroglycanopathy, an autosomal recessive disease, is associated with the
development of a variety of diseases, including muscular dystrophy. In humans, α …