Exosomes mediate intercellular microRNA delivery between hepatic stellate cells (HSC), the
principal fibrosis‐producing cells in the liver. The purpose of this study was to identify …

Abstract Hepatocyte exosomes (Exo Hep) are proposed to mediate physiological or
pathophysiological signaling in a variety of hepatic target cells. Exo Hep were purified from …

Background Hepatic stellate cell (HSC) differentiation/activation is central to liver fibrosis
and is innately linked to the immune response to liver injury. Exosomes (EXOs) are …

Hepatic fibrosis occurs during chronic hepatic injury and is involved in hepatic stellate cells
(HSCs) activated by several types of immune cells. Among the immune cells, hepatic …

Liver fibrosis is a global health problem caused by chronic liver injury resulting from various
factors. Hepatic stellate cells (HSCs) have been found to play a major role in liver fibrosis …

Exosomes are cell-derived extracellular vesicles thought to promote intercellular
communication by delivering specific content to target cells. The aim of this study was to …

The mechanism of exosomes derived from activated hepatic stellate cells (HSCs) involved in
liver fibrosis is poorly understood. We previously reported that hypoxia‐inducible factor 1 …

Fibrogenic pathways in the liver are principally regulated by activation of hepatic stellate
cells (HSC). Fibrosis is associated with chronic hepatitis C virus (HCV) infection, although …

Background Fibrogenic pathways in the liver are principally regulated by hepatic stellate
cells (HSC), which produce and respond to fibrotic mediators such as connective tissue …

Liver fibrosis occurs in response to chronic liver injury and is characterized by an excessive
deposition of extracellular matrix. Activated hepatic stellate cells are primarily responsible for …