Optical diffraction tomography techniques for the study of cell pathophysiology

K Kim, J Yoon, S Shin, SY Lee, SA Yang… - Journal of Biomedical …, 2016 - cyberleninka.ru
Three-dimensional imaging of biological cells is crucial for the investigation of cell biology,
providing valuable information to reveal the mechanisms behind pathophysiology of cells …

Three‐dimensional correlative single‐cell imaging utilizing fluorescence and refractive index tomography

M Schürmann, G Cojoc, S Girardo… - Journal of …, 2018 - Wiley Online Library
Cells alter the path of light, a fact that leads to well‐known aberrations in single cell or tissue
imaging. Optical diffraction tomography (ODT) measures the biophysical property that …

Optical diffraction tomography for high resolution live cell imaging

Y Sung, W Choi, C Fang-Yen, K Badizadegan… - Optics express, 2009 - opg.optica.org
We report the experimental implementation of optical diffraction tomography for quantitative
3D mapping of refractive index in live biological cells. Using a heterodyne Mach-Zehnder …

Optical diffraction tomography using a digital micromirror device for stable measurements of 4D refractive index tomography of cells

S Shin, K Kim, T Kim, J Yoon, K Hong… - … Phase Imaging II, 2016 - spiedigitallibrary.org
Optical diffraction tomography (ODT) is an interferometric microscopy technique capable of
measuring 3-D refractive index (RI) distribution of transparent samples. Multiple 2-D …

Correlative three-dimensional fluorescence and refractive index tomography: bridging the gap between molecular specificity and quantitative bioimaging

K Kim, WS Park, S Na, S Kim, T Kim… - Biomedical optics …, 2017 - opg.optica.org
Optical diffraction tomography (ODT) provides label-free three-dimensional (3D) refractive
index (RI) measurement of biological samples. However, due to the nature of the RI values …

Real-time visualization of 3-D dynamic microscopic objects using optical diffraction tomography

K Kim, KS Kim, HJ Park, JC Ye, YK Park - Optics express, 2013 - opg.optica.org
3-D refractive index (RI) distribution is an intrinsic bio-marker for the chemical and structural
information about biological cells. Here we develop an optical diffraction tomography …

High-speed in vitro intensity diffraction tomography

J Li, A Matlock, Y Li, Q Chen, C Zuo… - Advanced …, 2019 - spiedigitallibrary.org
We demonstrate a label-free, scan-free intensity diffraction tomography technique utilizing
annular illumination (aIDT) to rapidly characterize large-volume three-dimensional (3-D) …

Transport of intensity diffraction tomography with non-interferometric synthetic aperture for three-dimensional label-free microscopy

J Li, N Zhou, J Sun, S Zhou, Z Bai, L Lu… - Light: Science & …, 2022 - nature.com
We present a new label-free three-dimensional (3D) microscopy technique, termed transport
of intensity diffraction tomography with non-interferometric synthetic aperture (TIDT-NSA) …

Common-path diffraction optical tomography for investigation of three-dimensional structures and dynamics of biological cells

Y Kim, H Shim, K Kim, HJ Park, JH Heo, J Yoon… - Optics express, 2014 - opg.optica.org
We present an optical holographic micro-tomographic technique for imaging both the three-
dimensional structures and dynamics of biological cells. Optical light field images of a …

Tomographic diffractive microscopy of living cells based on a common-path configuration

WC Hsu, JW Su, TY Tseng, KB Sung - Optics letters, 2014 - opg.optica.org
We demonstrate a common-path tomographic diffractive microscopy technique for three-
dimensional (3D) refractive-index (RI) imaging of unstained living cells. A diffraction grating …