The inflammatory response in psoriasis: a comprehensive review

Y Deng, C Chang, Q Lu - Clinical reviews in allergy & immunology, 2016 - Springer
Psoriasis is a chronic inflammatory autoimmune disease characterized by an excessively
aberrant hyperproliferation of keratinocytes. The pathogenesis of psoriasis is complex and …

Progress in understanding the immunopathogenesis of psoriasis

RKH Mak, C Hundhausen, FO Nestle - Actas dermo-sifiliograficas, 2009 - Elsevier
This review emphasizes how translation from bench research to clinical knowledge and vice
versa has resulted in considerable progress in understanding the immunopathogenesis of …

Cytokines in psoriasis

CC de Alcantara, EMV Reiche, ANC Simão - Advances in clinical chemistry, 2021 - Elsevier
Psoriasis is chronic, immune-mediated, inflammatory disease with a multifactorial etiology
that affects the skin tissue and causes the appearance of dry and scaly lesions of anywhere …

Psoriasis: emerging therapeutic strategies

AB Gottlieb - Nature reviews Drug discovery, 2005 - nature.com
Psoriasis is a chronic inflammatory skin disorder that is characterized by thickened, scaly
plaques, and is estimated to affect∼ 1–3% of the Caucasian population. Traditional …

Psoriasis: from pathogenesis to novel therapeutic approaches

G Monteleone, F Pallone, TT MacDonald… - Clinical …, 2011 - portlandpress.com
Psoriasis is one of the commonest chronic inflammatory disorders. Its cause is unknown, but
a wealth of studies indicate that the disease results from a complex and dynamic interplay …

Novel immunotherapies for psoriasis

K Asadullah, HD Volk, W Sterry - TRENDS in Immunology, 2002 - cell.com
New insights into the pathophysiology of psoriasis have suggested possibilities for targeted
therapeutic intervention. Several novel, systemic immunomodulatory therapies are currently …

Insights into interplay of immunopathophysiological events and molecular mechanistic cascades in psoriasis and its associated comorbidities

AK Srivastava, TC Yadav, HK Khera, P Mishra… - Journal of …, 2021 - Elsevier
Psoriasis is an inflammatory skin disease with complex pathogenesis and multiple
etiological factors. Besides the essential role of autoreactive T cells and constellation of …

Orchestrated cytokines mediated by biologics in psoriasis and its mechanisms of action

AA Mohd Noor, M Azlan, N Mohd Redzwan - Biomedicines, 2022 - mdpi.com
Psoriasis is an autoimmune disease mediated by disturbed T cells and other immune cells,
and is defined by deep-red, well-demarcated skin lesions. Due to its varied etiologies and …

Psoriasis: from pathogenesis to targeted therapies

C Conrad, M Gilliet - Clinical reviews in allergy & immunology, 2018 - Springer
Over the last decade, the management of psoriasis has witnessed a paradigm shift. Thanks
to the increasing knowledge about the pathogenesis of psoriasis, targeted treatments with …

Key signaling pathways in psoriasis: recent insights from antipsoriatic therapeutics

H Ben Abdallah, C Johansen… - Psoriasis: Targets and …, 2021 - Taylor & Francis
Psoriasis is a common chronic inflammatory skin disease associated with several
comorbidities and reduced quality of life. In the past decades, highly effective targeted …