[HTML][HTML] Multiple active site residues are important for photochemical efficiency in the light-activated enzyme protochlorophyllide oxidoreductase (POR)

BRK Menon, SJO Hardman, NS Scrutton… - … of Photochemistry and …, 2016 - Elsevier
Protochlorophyllide oxidoreductase (POR) catalyzes the light-driven reduction of
protochlorophyllide (Pchlide), an essential, regulatory step in chlorophyll biosynthesis. The …

Mechanistic implications of the ternary complex structural models for the photoenzyme protochlorophyllide oxidoreductase

A Taylor, S Zhang, LO Johannissen… - The FEBS …, 2024 - Wiley Online Library
The photoenzyme protochlorophyllide oxidoreductase (POR) is an important enzyme for
understanding biological H‐transfer mechanisms. It uses light to catalyse the reduction of …

[HTML][HTML] Mechanistic reappraisal of early stage photochemistry in the light-driven enzyme protochlorophyllide oxidoreductase

DJ Heyes, SJO Hardman, D Mansell, JM Gardiner… - 2012 - journals.plos.org
The light-driven enzyme protochlorophyllide oxidoreductase (POR) catalyzes the reduction
of protochlorophyllide (Pchlide) to chlorophyllide (Chlide). This reaction is a key step in the …

[HTML][HTML] Mutagenesis alters the catalytic mechanism of the light-driven enzyme protochlorophyllide oxidoreductase

BRK Menon, PA Davison, CN Hunter… - Journal of Biological …, 2010 - ASBMB
The light-activated enzyme protochlorophyllide oxidoreductase (POR) catalyzes an
essential step in the synthesis of the most abundant pigment on Earth, chlorophyll. This …

Theoretical model of the protochlorophyllide oxidoreductase from a hierarchy of protocols

S Gholami, A Nenov, I Rivalta, M Bocola… - The Journal of …, 2018 - ACS Publications
The enzyme protochlorophyllide oxidoreductase (LPOR) catalyzes the light-driven reduction
of protochlorophyllide (Pchlide), a crucial step in chlorophyll biosynthesis. Molecular …

Protochlorophyllide oxidoreductase:“dark” reactions of a light-driven enzyme

DJ Heyes, AV Ruban, CN Hunter - Biochemistry, 2003 - ACS Publications
The light-driven enzyme NADPH: protochlorophyllide oxidoreductase (POR) catalyzes the
reduction of protochlorophyllide (Pchlide) to chlorophyllide (Chlide), a key regulatory step in …

Conformational Events during Ternary Enzyme− Substrate Complex Formation Are Rate Limiting in the Catalytic Cycle of the Light-Driven Enzyme Protochlorophyllide …

DJ Heyes, BRK Menon, M Sakuma, NS Scrutton - Biochemistry, 2008 - ACS Publications
The light-driven enzyme, protochlorophyllide oxidoreductase (POR), has proven to be an
excellent model system for studying the role of protein motions during catalysis. POR …

Identification and characterization of the product release steps within the catalytic cycle of protochlorophyllide oxidoreductase

DJ Heyes, CN Hunter - Biochemistry, 2004 - ACS Publications
The chlorophyll biosynthetic enzyme protochlorophyllide reductase (POR) catalyzes the
reduction of protochlorophyllide (Pchlide) into chlorophyllide (Chlide) with reduced …

[HTML][HTML] Cryogenic and laser photoexcitation studies identify multiple roles for active site residues in the light-driven enzyme protochlorophyllide oxidoreductase

BRK Menon, JP Waltho, NS Scrutton… - Journal of Biological …, 2009 - ASBMB
The light-activated enzyme NADPH-protochlorophyllide oxidoreductase (POR) catalyzes the
trans addition of hydrogen across the C-17–C-18 double bond of protochlorophyllide …

[HTML][HTML] Elucidating substrate binding in the light-dependent protochlorophyllide oxidoreductase

P Pesara, K Szafran, HC Nguyen, A Sirohiwal… - Chemical …, 2024 - pubs.rsc.org
The Light-Dependent Protochlorophyllide Oxidoreductase (LPOR) catalyzes a crucial step in
chlorophyll biosynthesis: the rare biological photocatalytic reduction of the double CC bond …