Pain, by definition, is a subjective experience, and as such its presence has usually been
based on a self-report. However, limitations of self-reports for pain diagnostics, particularly …

The assessment of chronic pain is a highly unmet medical need. Chronic pain is also the
subject of a large and costly category of legal claims. Yet, with pain cases, the jury always …

Arguments made for the advantages of replacing pain ratings with brain-imaging data
include assumptions that pain ratings are less reliable and objective and that brain image …

There is increasing pressure from the general public, clinical and scientific circles, insurance
companies, and legal, government, and military agencies to adopt brain imaging for chronic …

“Ouch!” This is a primal, intuitive, and fundamental expression of pain. We all say it, and we
all know what it signifies. For centuries, scientists have struggled to elucidate the neural …

Chronic pain is the greatest source of disability globally and claims related to chronic pain
feature in many insurance and medico-legal cases. Brain imaging (for example, functional …

We intuitively understand what is meant by the term ''disease.''Surprisingly though, there is
no agreement as to the precise definition of a ''disease.''10 Definitions and classifications are …

Human brain imaging studies have identified multiple brain regions activated during the
experience of pain. Do these complex activation patterns lead to confusion and an …

In this article, I review the concept of personalized pain management and consider how
brain imaging and quantitative sensory testing can be used to derive biomarkers of chronic …

Non-invasive functional brain imaging is used more than ever to investigate pain in health
and disease, with the prospect of finding new means to alleviate pain and improve patient …