[HTML][HTML] General intelligence is associated with subclinical inflammation in Nepalese children: a population-based plasma proteomics study
Improving child cognition in impoverished countries is a public health priority. Yet, biological
pathways and associated biomarkers of impaired cognition remain poorly understood and …
pathways and associated biomarkers of impaired cognition remain poorly understood and …
Plasma proteome biomarkers of inflammation in school aged children in Nepal
Inflammation is a condition stemming from complex host defense and tissue repair
mechanisms, often simply characterized by plasma levels of a single acute reactant. We …
mechanisms, often simply characterized by plasma levels of a single acute reactant. We …
Label free quantitative proteomic profiling of serum samples of intellectually disabled young patients revealed dysregulation of complement coagulation and …
Intellectual disability is a heterogeneous disorder, diagnosed using intelligence quotient (IQ)
score criteria. Currently, no specific clinical test is available to diagnose the disease and its …
score criteria. Currently, no specific clinical test is available to diagnose the disease and its …
Serum biomarkers to mild cognitive deficits in children and adolescents
L Tuon, NS Tramontin, I Custódio, VH Comim… - Molecular …, 2023 - Springer
Intellectual disability (ID) is a condition characterized by significant limitations in both
cognitive development and adaptive behavior. The diagnosis is made through clinical …
cognitive development and adaptive behavior. The diagnosis is made through clinical …
[HTML][HTML] Systemic inflammation during the first year of life is associated with brain functional connectivity and future cognitive outcomes
The first years of life are a sensitive period of rapid neural and immune system development
vulnerable to the impact of adverse experiences. Several studies support inflammation as a …
vulnerable to the impact of adverse experiences. Several studies support inflammation as a …
[HTML][HTML] The plasma proteome is associated with anthropometric status of undernourished Nepalese school-aged children
Background Malnutrition affects body growth, size, and composition of children. Yet, few
functional biomarkers are known to be associated with childhood morphology. Objective …
functional biomarkers are known to be associated with childhood morphology. Objective …
Socioeconomic status and early blood concentrations of inflammation-related and neurotrophic proteins among extremely preterm newborns
The main objective of this study was to evaluate the relationship between mother's
socioeconomic disadvantage and blood concentrations of inflammation-related proteins …
socioeconomic disadvantage and blood concentrations of inflammation-related proteins …
[HTML][HTML] Association of gut microbiota, plasma and fecal metabolite profiles with intellectual development in school-age children
Y Zhou, K Zhou, X Lin, Y Wei, B Ma, S Lu… - Translational …, 2023 - ncbi.nlm.nih.gov
Background Little is known about how the gut microbiota and metabolic profiles are related
to cognitive outcomes in young children until now. It was hypothesized that the gut …
to cognitive outcomes in young children until now. It was hypothesized that the gut …
Socioeconomic disadvantage moderates the association between peripheral biomarkers and childhood psychopathology
Background Socioeconomic disadvantage (SED) has been consistently associated with
early life mental health problems. SED has been shown to impact multiple biological …
early life mental health problems. SED has been shown to impact multiple biological …
[HTML][HTML] Early life inflammation and neurodevelopmental outcome in Bangladeshi infants growing up in adversity
Exposure to profound adversity can negatively affect the neurodevelopment of children, but
biologic mechanisms that underlie this association remain unknown. We sought to …
biologic mechanisms that underlie this association remain unknown. We sought to …