[HTML][HTML] Focus: the aging brain: the significance of the default mode network (DMN) in neurological and neuropsychiatric disorders: a review

A Mohan, AJ Roberto, A Mohan, A Lorenzo… - The Yale journal of …, 2016 - ncbi.nlm.nih.gov
The relationship of cortical structure and specific neuronal circuitry to global brain function,
particularly its perturbations related to the development and progression of neuropathology …

Default-mode brain dysfunction in mental disorders: a systematic review

SJ Broyd, C Demanuele, S Debener, SK Helps… - … & biobehavioral reviews, 2009 - Elsevier
In this review we are concerned specifically with the putative role of the default-mode
network (DMN) in the pathophysiology of mental disorders. First, we define the DMN concept …

The default mode network in healthy aging and Alzheimer′ s disease

K Mevel, G Chételat, F Eustache… - International journal of …, 2011 - Wiley Online Library
In the past decade, a “default mode network”(DMN) has been highlighted in neuroimaging
studies as a set of brain regions showing increased activity in task‐free state compared to …

The role of default network deactivation in cognition and disease

A Anticevic, MW Cole, JD Murray, PR Corlett… - Trends in cognitive …, 2012 - cell.com
A considerable body of evidence has accumulated over recent years on the functions of the
default-mode network (DMN)–a set of brain regions whose activity is high when the mind is …

Resting-state glutamate and GABA concentrations predict task-induced deactivation in the default mode network

Y Hu, X Chen, H Gu, Y Yang - Journal of Neuroscience, 2013 - Soc Neuroscience
Deactivation of the human brain's default mode network (DMN) is regarded as suppression
of endogenous activity to support exogenous task-related processes. This phenomenon has …

Functional disintegration of the default mode network in prodromal Alzheimer's disease

KNH Dillen, HIL Jacobs, J Kukolja… - Journal of …, 2017 - content.iospress.com
Neurodegenerative brain changes can affect the functional connectivity strength between
nodes of the default-mode network (DMN), which may underlie changes in cognitive …

Alzheimer's disease and amnestic mild cognitive impairment weaken connections within the default-mode network: a multi-modal imaging study

DC Zhu, S Majumdar, IO Korolev… - Journal of …, 2013 - content.iospress.com
We applied a multi-modal imaging approach to examine structural and functional alterations
in the default-mode network (DMN) that are associated with Alzheimer's disease (AD) and …

Longitudinal assessment of default-mode brain function in aging

J Persson, S Pudas, LG Nilsson, L Nyberg - Neurobiology of aging, 2014 - Elsevier
Age-related changes in the default-mode network (DMN) have been identified in prior cross-
sectional functional magnetic resonance imaging studies. Here, we investigated longitudinal …

Constituents and functional implications of the rat default mode network

LM Hsu, X Liang, H Gu, JK Brynildsen… - Proceedings of the …, 2016 - National Acad Sciences
The default mode network (DMN) has been suggested to support a variety of self-referential
functions in humans and has been fractionated into subsystems based on distinct responses …

Intracranial electrophysiology of the human default network

KCR Fox, BL Foster, A Kucyi, AL Daitch… - Trends in cognitive …, 2018 - cell.com
The human default network (DN) plays a critical role in internally directed cognition,
behavior, and neuropsychiatric disease. Despite much progress with functional …