Caveolae: one function or many?

JPX Cheng, BJ Nichols - Trends in cell biology, 2016 - cell.com
Caveolae are small, bulb-shaped plasma membrane invaginations. Mutations that ablate
caveolae lead to diverse phenotypes in mice and humans, making it challenging to uncover …

The multiple faces of caveolae

RG Parton, K Simons - Nature reviews Molecular cell biology, 2007 - nature.com
Caveolae are a highly abundant but enigmatic feature of mammalian cells. They form
remarkably stable membrane domains at the plasma membrane but can also function as …

Caveolae: structure, function, and relationship to disease

RG Parton - Annual review of cell and developmental biology, 2018 - annualreviews.org
The plasma membrane of eukaryotic cells is not a simple sheet of lipids and proteins but is
differentiated into subdomains with crucial functions. Caveolae, small pits in the plasma …

Caveolae and lipid sorting: Shaping the cellular response to stress

RG Parton, MM Kozlov, N Ariotti - Journal of Cell Biology, 2020 - rupress.org
Caveolae are an abundant and characteristic surface feature of many vertebrate cells. The
uniform shape of caveolae is characterized by a bulb with consistent curvature connected to …

Caveolae–mechanosensitive membrane invaginations linked to actin filaments

A Echarri, MA Del Pozo - Journal of cell science, 2015 - journals.biologists.com
An essential property of the plasma membrane of mammalian cells is its plasticity, which is
required for sensing and transmitting of signals, and for accommodating the tensional …

Caveolae: Formation, dynamics, and function

RG Parton, KA McMahon, Y Wu - Current opinion in cell biology, 2020 - Elsevier
Caveolae are abundant surface pits formed by the assembly of cytoplasmic proteins on a
platform generated by caveolin integral membrane proteins and membrane lipids. This …

Stressing caveolae new role in cell mechanics

P Nassoy, C Lamaze - Trends in cell biology, 2012 - cell.com
It has been almost 60 years since caveolae were first visualized by Eichi Yamada and
George Palade. Nevertheless, these specialized invaginations of the plasma membrane …

[PDF][PDF] Caveolae

RG Parton, VA Tillu, BM Collins - Current biology, 2018 - cell.com
Caveolae are one of the most abundant and striking features of the plasma membrane of
many mammalian cell types. These surface pits have fascinated biologists since their …

The caveolae dress code: structure and signaling

C Lamaze, N Tardif, M Dewulf, S Vassilopoulos… - Current opinion in cell …, 2017 - Elsevier
Over the past decade, interest in caveolae biology has peaked. These small bulb-shaped
plasma membrane invaginations of 50–80 nm diameter present in most cell types have …

Caveolae: anchored, multifunctional platforms in the lipid ocean

B Van Deurs, K Roepstorff, AM Hommelgaard… - Trends in cell …, 2003 - cell.com
The function of caveolae is hotly debated. It now seems clear that caveolae are stable
membrane domains that are kept in place by the actin cytoskeleton. However, this stability …