Little is known about the functions of microRNAs (miRNAs) in skin pigmentation disorders.
The aim of this study was to investigate the expression and potential role of miRNAs in …

Vitiligo is an autoimmune skin disease characterized by presence of pale patchy areas of
depigmentation. MicroRNAs (miRNAs) are important regulators of gene expression and play …

Vitiligo is a common chronic depigmented skin disease characterized by melanocyte loss or
dysfunction in the lesion. The pathogenesis of vitiligo has not been fully clarified. Most …

Background Epigenetics of vitiligo was evaluated in few studies. In particular, the role of miR-
21, a microRNA involved in various processes, including melanogenesis, was never …

It has been reported that loss and degradation of epidermal melanocytes is closely
associated with the pathogenesis of vitiligo. In addition, CD8+ T and regulatory T (Treg) cells …

Microphthalmia-associated transcription factor (MITF) is a master regulatory factor for
melanocytes. MITF regulates multiple pigmentary genes for maintaining cellular …

Vitiligo is an acquired skin disorder clinically characterized by the progressive appearance
of white maculae due to a loss of functioning epidermal melanocytes. Studies have shown …

Micro RNA s are known to be the important regulators of skin physiology and considered as
new therapeutic targets to treat skin diseases. In this study, miR‐125b was identified as a …

Background miRNAs are small non-coding RNA molecules that post-transcriptionally
regulate gene expression. We have earlier reported the skin miRNA expression profiling in …

Vitiligo is considered a disabling disease that affects physical, social, psychological, and
occupational aspects of an individual's quality of life. The search for non-invasive and …