Background Glial activation and neuroinflammation in the spinal trigeminal nucleus (STN)
play a pivotal role in the genesis and maintenance of trigeminal neuralgia (TN). Resveratrol …

Trigeminal neuralgia (TN) is a common type of neuropathic pain whereas the underlying
pathogenesis has not been completely elucidated. Recent study suggests that the …

Background Resveratrol, a component of red wine, has been reported to decrease
prostaglandin E2 production by inhibiting the cyclooxygenase-2 cascade and to modulate …

Background Although we have previously reported that intravenous resveratrol
administration inhibits the nociceptive neuronal activity of spinal trigeminal nucleus caudalis …

The present study aimed to investigate the effect of resveratrol on inflammatory pain. Mice
were injected intraperitoneally with lipopolysaccharide (LPS) for 5 consecutive days to …

Anti-inflammatory activity of resveratrol has been widely studied, while its beneficial effect on
the management of neuropathic pain, a refractory chronic syndrome with pro-inflammation …

Background and Purpose Patients suffering from trigeminal neuralgia are often
accompanied by anxiety and depression. Microglia‐mediated neuroinflammation is involved …

Exaggerated inflammatory responses in microglia represent one of the major risk factors for
various central nervous system's (CNS) associated pathologies. Release of excessive …

Background We aimed to investigate the potential prophylactic and curative effects of
rosmarinic acid, one of the main constituents of rosemary, on the neuropathic pain induced …

Abstract Ginsenoside-Rb1 (Rb1) has anti-inflammatory effects. However, the potential
antinociceptive value of Rb1 for the treatment of acute inflammatory nociception is still …