There is mounting evidence that 5-hydroxytryptamine (5-HT) plays a role in asthma.
However, scarce information exists about the pulmonary expression of 5-HT receptors and …

The present study was undertaken to evaluate the effects of 5-hydroxytryptamine on
pulmonary vascular resistances and vascular permeability with respect to the 5 …

5-hydroxytryptamine (5-HT) has been reported to show some effects in respiratory tissues by
activation of different subtype receptors. It has been demonstrated that 5-HT2 receptor …

Serotonin (5-hydroxytryptamine [5-HT]) is a multifunctional amine with wide occurrence in
both neural and non-neural tissues, including the lung. The diverse responses to 5-HT are …

Background A possible role of 5‐hydroxytryptamine (5‐HT) in the origin of antigen‐induced
airway hyperresponsiveness (AI‐AHR) has been scarcely investigated. Objective To explore …

C57BL/6 mice exhibit acute transient decreases in lung conductance (GL) and dynamic
compliance (Cdyn) after intravenous administration of serotonin (5-HT). To identify the …

Asthma is an inflammatory disease of the lung characterized by airways hyper-
responsiveness (AHR), inflammation, and mucus hyperproduction. Current mainstream …

Background Chronic obstructive pulmonary disease (COPD) arises from an interaction
between genetic host factors and environmental exposures (mainly cigarette smoke (CS)) …

The isolated perfused guine apig lung was used to investigate pharmacologic
characteristics of serotonin receptors in pulmonary vascular and airway smooth muscle …

The 5‐HT receptor subtype that mediates bronchocontraction and the involvement of
neuronal and non‐neuronal acetylcholine was assessed in murine isolated tracheae …