[HTML][HTML] ST3Gal III modulates breast cancer cell adhesion and invasion by altering the expression of invasion-related molecules

HX Cui, H Wang, Y Wang, J Song… - Oncology …, 2016 - spandidos-publications.com
Abstract Changes in the carbohydrate structure on the surface of tumor cells is an important
feature of cancer metastasis. The specific role of sialic acids in the glycoconjugate terminal …

α2, 3-Sialyltransferase ST3Gal IV promotes migration and metastasis in pancreatic adenocarcinoma cells and tends to be highly expressed in pancreatic …

M Pérez-Garay, B Arteta, E Llop, L Cobler… - The international journal …, 2013 - Elsevier
Sialyltransferases have received much attention recently as they are frequently up-regulated
in cancer cells. However, the role played by each sialyltransferase in tumour progression is …

[HTML][HTML] α2,3-Sialyltransferase ST3Gal III Modulates Pancreatic Cancer Cell Motility and Adhesion In Vitro and Enhances Its Metastatic Potential In Vivo

M Pérez-Garay, B Arteta, L Pagès, R de Llorens… - PloS one, 2010 - journals.plos.org
Background Cell surface sialylation is emerging as an important feature of cancer cell
metastasis. Sialyltransferase expression has been reported to be altered in tumours and …

Cell surface α2, 6-sialylation affects adhesion of breast carcinoma cells

S Lin, W Kemmner, S Grigull, PM Schlag - Experimental cell research, 2002 - Elsevier
Tumor-associated alterations of cell surface glycosylation play a crucial role in the adhesion
and metastasis of carcinoma cells. The aim of this study was to examine the effect of α2, 6 …

α2, 6-linked sialic acids on N-glycans modulate the adhesion of hepatocarcinoma cells to lymph nodes

S Wang, X Chen, A Wei, X Yu, B Niang, J Zhang - Tumor Biology, 2015 - Springer
The alterations of cell surface sialylation play a key role in tumor metastasis. Enhanced α2, 6-
sialylation on N-glycans results from overexpression of the sialyltransferase ST6Gal-I. Hca-F …

Modification of α2,6‐sialylation mediates the invasiveness and tumorigenicity of non‐small cell lung cancer cells in vitro and in vivo via Notch1/Hes1/MMPs pathway

Q Yuan, X Chen, Y Han, T Lei, Q Wu… - … journal of cancer, 2018 - Wiley Online Library
The alterations of sialylation on cell surface N‐glycans due to overexpression of different
sialyltransferases play a vital role in tumorigenesis and tumor progression. The β …

[HTML][HTML] Knockdown of ST6Gal-I increases cisplatin sensitivity in cervical cancer cells

X Zhang, C Pan, L Zhou, Z Cai, S Zhao, D Yu - BMc cancer, 2016 - Springer
Abstract Background Sialyltransferase I (ST6Gal-I) is an enzyme involved in tumor
metastasis that processes sialic acid precursors into their mature form, enabling them to …

[HTML][HTML] Knockdown of α2, 3-sialyltransferases impairs pancreatic cancer cell migration, invasion and e-selectin-dependent adhesion

PE Guerrero, L Miró, BS Wong, A Massaguer… - International journal of …, 2020 - mdpi.com
Aberrant sialylation is frequently found in pancreatic ductal adenocarcinoma (PDA). α2, 3-
Sialyltransferases (α2, 3-STs) ST3GAL3 and ST3GAL4 are overexpressed in PDA tissues …

ST6GALNAC1 promotes the invasion and migration of breast cancer cells via the EMT pathway

Y Luo, H Cao, C Lei, J Liu - Genes & Genomics, 2023 - Springer
Background A specific sialyl-transferases called ST6GALNAC1 has been proven to up-
regulate abnormal O‐glycosylation, which is strongly associated with tumorigenesis and …

Soyasaponin I decreases the expression of α2, 3-linked sialic acid on the cell surface and suppresses the metastatic potential of B16F10 melanoma cells

WW Chang, CY Yu, TW Lin, PH Wang… - … and biophysical research …, 2006 - Elsevier
The transfer of sialic acids to the non-reducing terminal positions on sugar chains of
glycoconjugates is catalyzed by sialyltransferases (STs). Increased sialylation is correlated …