[HTML][HTML] Fatty acid desaturases, polyunsaturated fatty acid regulation, and biotechnological advances

JM Lee, H Lee, SB Kang, WJ Park - Nutrients, 2016 - mdpi.com
Polyunsaturated fatty acids (PUFAs) are considered to be critical nutrients to regulate human
health and development, and numerous fatty acid desaturases play key roles in synthesizing …

[HTML][HTML] Biological role of unsaturated fatty acid desaturases in health and disease

A Czumaj, T Śledziński - Nutrients, 2020 - mdpi.com
Polyunsaturated fatty acids (PUFAs) are considered one of the most important components
of cells that influence normal development and function of many organisms, both eukaryotes …

Polyunsaturated fatty acids: biochemical, nutritional and epigenetic properties

P Benatti, G Peluso, R Nicolai… - Journal of the American …, 2004 - Taylor & Francis
Dietary polyunsaturated fatty acids (PUFA) have effects on diverse physiological processes
impacting normal health and chronic diseases, such as the regulation of plasma lipid levels …

Recent advances in the study of fatty acid desaturases from animals and lower eukaryotes

SL Pereira, AE Leonard, P Mukerji - Prostaglandins, Leukotrienes and …, 2003 - Elsevier
The biosynthesis of polyunsaturated fatty acids (PUFAs) in different organisms can involve a
variety of pathways, catalyzed by a complex series of desaturation and elongation steps. A …

[HTML][HTML] Diet regulation of long-chain PUFA synthesis: role of macronutrients, micronutrients, and polyphenols on Δ-5/Δ-6 desaturases and elongases 2/5

M Gonzalez-Soto, DM Mutch - Advances in Nutrition, 2021 - Elsevier
Deficiencies in the n–3 (ω-3) long-chain PUFAs (LC-PUFAs) EPA and DHA are associated
with increased risk for the development of numerous diseases. Although n–3 LC-PUFAs can …

[HTML][HTML] Dietary ω3-and ω6-Polyunsaturated fatty acids reconstitute fertility of Juvenile and adult Fads2-Deficient mice

W Stoffel, I Schmidt-Soltau, E Binczek, A Thomas… - Molecular …, 2020 - Elsevier
Abstract Objective Polyunsaturated fatty acids (PUFAs), including essential fatty acids
linoleic and α-linolenic acid and derived long chain and very long chain ω3-and ω6 …

Polyunsaturated fatty acids: biotechnology

D Warude, K Joshi, A Harsulkar - Critical reviews in biotechnology, 2006 - Taylor & Francis
Polyunsaturated fatty acids like EPA and DHA have attracted a great attention due to their
beneficial effects on human health. At present, fish oil is the major source of EPA and DHA …

Unsaturated fatty acids, desaturases, and human health

H Lee, WJ Park - Journal of medicinal food, 2014 - liebertpub.com
With the increasing concern for health and nutrition, dietary fat has attracted considerable
attention. The composition of fatty acids in a diet is important since they are associated with …

Enzymes for transgenic biosynthesis of long-chain polyunsaturated fatty acids

YS Huang, SL Pereira, AE Leonard - Biochimie, 2004 - Elsevier
Polyunsaturated fatty acids (PUFAs) are important for the normal development and function
of all organisms, and are essential in maintaining human health. Impaired PUFA metabolism …

Nutrigenomics and nutrigenetics of ω3 polyunsaturated fatty acids

JPV Heuvel - Progress in molecular biology and translational …, 2012 - Elsevier
Diets rich in ω3 polyunsaturated fatty acids (ω3-PUFAs) such as alpha-linolenic acid,
eicosapentaenoic acid, and docosahexaenoic acid are associated with decreased …