[HTML][HTML] FoxO1 in dopaminergic neurons regulates energy homeostasis and targets tyrosine hydroxylase
Dopaminergic (DA) neurons are involved in the integration of neuronal and hormonal
signals to regulate food consumption and energy balance. Forkhead transcriptional factor …
signals to regulate food consumption and energy balance. Forkhead transcriptional factor …
Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis
Insulin signaling in the hypothalamus plays a role in maintaining body weight. Studies
suggest that the forkhead transcription factor Foxo1 is an important mediator of insulin …
suggest that the forkhead transcription factor Foxo1 is an important mediator of insulin …
[HTML][HTML] FOXO1 in the ventromedial hypothalamus regulates energy balance
The transcription factor FOXO1 plays a central role in metabolic homeostasis by regulating
leptin and insulin activity in many cell types, including neurons. However, the neurons …
leptin and insulin activity in many cell types, including neurons. However, the neurons …
Preserved energy balance in mice lacking FoxO1 in neurons of Nkx2. 1 lineage reveals functional heterogeneity of FoxO1 signaling within the hypothalamus
G Heinrich, K Meece, SL Wardlaw, D Accili - Diabetes, 2014 - Am Diabetes Assoc
Transcription factor forkhead box O1 (FoxO1) regulates energy expenditure (EE), food
intake, and hepatic glucose production. These activities have been mapped to specific …
intake, and hepatic glucose production. These activities have been mapped to specific …
Inhibition of hypothalamic Foxo1 expression reduced food intake in diet‐induced obesity rats
Insulin signalling in the hypothalamus plays a role in maintaining body weight. The forkhead
transcription factor Foxo1 is an important mediator of insulin signalling in the hypothalamus …
transcription factor Foxo1 is an important mediator of insulin signalling in the hypothalamus …
Astrocytic FoxO1 in the hypothalamus regulates metabolic homeostasis by coordinating neuropeptide Y neuron activity
The forkhead box transcription factor O1 (FoxO1) is expressed ubiquitously throughout the
central nervous system, including in astrocytes, the most prevalent glial cell type in the brain …
central nervous system, including in astrocytes, the most prevalent glial cell type in the brain …
Overexpression of FoxO1 in the hypothalamus and pancreas causes obesity and glucose intolerance
HJ Kim, M Kobayashi, T Sasaki, O Kikuchi… - …, 2012 - academic.oup.com
Recent studies have revealed that insulin signaling in pancreatic β-cells and the
hypothalamus is critical for maintaining nutrient and energy homeostasis, the failure of which …
hypothalamus is critical for maintaining nutrient and energy homeostasis, the failure of which …
Blunted Refeeding Response and Increased Locomotor Activity in Mice Lacking FoxO1 in Synapsin-Cre–Expressing Neurons
H Ren, L Plum-Morschel, R Gutierrez-Juarez, TY Lu… - Diabetes, 2013 - Am Diabetes Assoc
Successful development of antiobesity agents requires detailed knowledge of neural
pathways controlling body weight, eating behavior, and peripheral metabolism. Genetic …
pathways controlling body weight, eating behavior, and peripheral metabolism. Genetic …
[HTML][HTML] Foxo1 regulates Dbh expression and the activity of the sympathetic nervous system in vivo
The transcription factor FoxO1 regulates multiple physiological processes. Here, we show
that FoxO1 is highly expressed in neurons of the locus coeruleus and of various sympathetic …
that FoxO1 is highly expressed in neurons of the locus coeruleus and of various sympathetic …
Roles of FoxO1 and Sirt1 in the central regulation of food intake
T Sasaki, T Kitamura - Endocrine journal, 2010 - jstage.jst.go.jp
The hypothalamus is the center of controlling food intake and energy expenditure by
integrating information on energy status, ie adiposity and nutrient signals. Especially, two …
integrating information on energy status, ie adiposity and nutrient signals. Especially, two …