Glycosylation is one of the most important posttranslational modifications of proteins and
lipids that contributes to the structural diversity of cellular molecules. Enzymes of the …

Background. Glycosylation is the most frequent posttranslational modification of proteins and
lipids influencing inter‐and intracellular communication and cell adhesion. Altered …

Alteration of protein O-glycosylation in various human cancers including breast cancer is
well known, but molecular roles of their aberrant glycosylations on cancer have not been …

Background The post-translational modification of proteins, including glycosylation, differs
between normal and tumor cells. The UDP-N-acetyl-D-galactosamine polypeptide N …

A number of glycosyltransferases have been identified and biologically characterized in
cancer cells, yet their exact pathophysiological functions are largely unknown. Here, we …

Breast cancer is the most lethal malignancy in women. N-acetylgalactosaminyltransferase 6
(GALNT6) is an enzyme which mediates the initial step of mucin-type O-glycosylation, and …

GALNT7 is a glycosyltransferase enzyme transferring N-acetylgalactosamine to initiate O-
linked glycosylation in the Golgi apparatus. Breast cancer is the most common cancer in …

Background: The post-translational modification of proteins, including glycosylation, is
known to differ between normal and tumour cells. In this study, the expression profile of two …

Abstract Polypeptide N‑acetylgalactosaminyltransferase 6 (GALNT6), which is involved in
the initiation of O‑glycosylation, has been reported to play crucial roles in mammary …

Aberrant expression of the polypeptide N-acetyl-galactosaminyltransferase (GALNTs) has
been associated with cancer, but their function (s) in metastasis remains elusive. We have …