Prostate cancer (PCa) is known to develop resistance to chemotherapy. Growth arrest‐
specific 6 (GAS6), plays a role in tumor progression by regulating growth in many cancers …

Our recent studies have shown that annexin II, expressed on the cell surface of osteoblasts,
plays an important role in the adhesion of hematopoietic stem cells (HSCs) to the endosteal …

Disseminated tumor cells (DTCs) are believed to lie dormant in the marrow before they can
be activated to form metastases. How DTCs become dormant in the marrow and how …

Although the generation of BCR-ABL is the molecular hallmark of chronic myeloid leukemia
(CML), the comprehensive molecular mechanisms of the disease remain unclear yet …

GAS6 and its receptors (Tryo 3, Axl, Mer or “TAM”) are known to play a role in regulating
tumor progression in a number of settings. Previously we have demonstrated that GAS6 …

Novel treatment targets must be discovered to improve the results for patients with prostate
cancer, which continues to be a significant worldwide health problem. Growth Arrest-Specific …

Abstract Growth arrest specific 2 (GAS2) modulates cell cycle, apoptosis, and Calpain
activity. GAS2–Calpain2 axis is required for the growth of BCR-ABL+ hematopoietic cells …

Men diagnosed with localized prostate cancer can develop metastases many years after
initial treatment, resulting in a poor prognosis. The purpose of this study was to investigate …

Introduction: As it is not clear whether growth arrest-specific 5 (GAS5) inhibits gastric cancer
(GC) cell proliferation by regulating cell cycle, we analyzed the effect of GAS5 on cell cycle …

Multiple myeloma is a mostly incurable malignancy characterized by the expansion of a
malignant plasma cell (PC) clone in the human bone marrow (BM). Myeloma cells closely …