Genome-wide association studies (GWAS) have identified a large number of disease-
associated SNPs, but in few cases the functional variant and the gene it controls have been …

Genome-wide association studies (GWAS) have identified more than 8900 genetic variants,
mainly single-nucleotide polymorphisms (SNPs), associated with hundreds of human traits …

Genome-wide association studies have been successful in identifying single nucleotide
polymorphisms (SNPs) associated with a large number of phenotypes. However, an …

The genome-wide association study (GWAS) is a powerful approach for studying the genetic
complexities of human disease. Unfortunately, GWASs often fail to identify clinically …

Background The number of genome-wide association studies (GWAS) is growing rapidly
leading to the discovery and replication of many new disease loci. Combining results from …

Genome-wide association studies have shown that the far majority of disease-associated
variants reside in the non-coding regions of the genome, suggesting that gene regulatory …

Genome-wide association studies have successfully identified numerous loci at which
common variants influence disease risk or quantitative traits. Despite these successes, the …

Genome-wide association studies (GWASs) have identified a multitude of genetic loci
involved with traits and diseases. However, it is often unclear which genes are affected in …

Genome wide association studies provide an unbiased discovery mechanism for numerous
human diseases. However, a frustration in the analysis of GWAS is that the majority of …

Background Genome wide association studies (GWAS) are a population-scale approach to
the identification of segments of the genome in which genetic variations may contribute to …