Trypanosoma cruzi, the causative agent of Chagas disease, is an obligatory intracellular
parasite with a digenetic life cycle. Due to the variety of host environments, it faces several …

Pathological processes such as bacterial, viral and parasitic infections can generate a
plethora of responses such as, but not restricted to, oxidative stress that can be harmful to …

Trypanosoma cruzi is exposed to oxidative stresses during its life cycle, and amongst the
strategies employed by this parasite to deal with these situations sits a peculiar …

Significance: Chagas disease (CD) affects several million people in Latin America and is
spreading beyond its classical boundaries due to the migration of infected host and insect …

Trypanosoma cruzi is the etiologic agent of Chagas' disease, an infection that affects several
million people in Latin America. With no immediate prospect of a vaccine and problems …

Components of the DNA mismatch repair (MMR) pathway are major players in processes
known to generate genetic diversity, such as mutagenesis and DNA recombination …

Trypanosoma cruzi, a parasitic protozoan, is the etiological agent of Chagas disease, an
endemic and neglected pathology in Latin America. It presents a life cycle that involves a …

The toxicity of oxygen and nitrogen reactive species appears to be merely the tip of the
iceberg in the world of redox homeostasis. Now, oxidative stress can be seen as a two-sided …

As an intracellular parasite, Trypanosoma cruzi is exposed to reactive oxygen species. The
study of the proteins involved in the hydroperoxide detoxification cascade, tryparedoxin …

Trypanosoma cruzi is the etiologic agent of Chagas' disease. Infected cells with T. cruzi
activate several responses that promote unbalance of reactive oxygen species (ROS) that …