Abstract Introduction: Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) is
characterized by the sudden onset of severe obsessive-compulsive symptoms and/or eating …

Depression is a common psychiatric disorder and a leading cause of disability worldwide.
Traditional Chinese medicine is one of the commonly used complementary and alternative …

Inflammatory immune activation has been frequently associated with the development of
major depression. Microglia might serve as an important interface in this immune system-to …

Background Clinical findings indicate heterogeneity of depressive disorders, stressing the
importance of subtyping depression for research and clinical care. Subtypes of the common …

This study was designed to investigate the effect of the cortical cyclooxygenase-2 (COX2)
pathway on depressive behaviour in rats. Meloxicam, COX2 overexpressed lentivirus and …

Objectives The breakthrough advancements in scientific medical research have greatly
improved our understanding of the pathogenesis of depression, encouraging drug …

Background: Depression is a common complication after stroke, and inflammation may be a
pathophysiological mechanism. This study examines whether anti-inflammatory treatment …

Objective: Accumulating evidence suggests that anti-inflammatory interventions can
modulate neuropsychiatric symptoms. Pediatric Acute-onset Neuropsychiatric Syndrome …

Cancer-related inflammation is an essential process in malignancies. Celecoxib, a
nonsteroidal anti-inflammatory drug that acts via the selective inhibition of cyclooxygenase …

Background Signs of an inflammatory process have been described in major depression.
Methods In a double-blind, randomized study of celecoxib or placebo add-on to reboxetine …