Duchenne Muscular Dystrophy (DMD) is a fatal skeletal muscle wasting disease
underpinned by extensive metabolic dysfunction. This culminates in reduced energy …

Introduction: Physical activity (PA), exercise, and lifestyle intervention are basic interventions
to reduce short-and long-term surgical and non-surgical complications in bariatric patients …

Purpose: To evaluate the effects of duodenal-jejunal bypass (DJB) on the diaphragm muscle
of obese rats fed on a western diet (WD). Methods: Eighteen male Wistar rats were fed a …

Muscle quality has been suggested to contribute to the age-related decline in muscle
function, which is exacerbated by obesity. Although the mechanism is unknown, it may be …

Exercise can prevent and treat metabolic diseases. This thesis aimed to study energy
metabolism in cultured human myotubes from subjects with different metabolic profile and …

The growing field of translational myology continually seeks to define and promote the
generalizability of muscle research to clinical practice via optimizing the transition of a wide …

The main aim of this thesis was to increase our understanding of the metabolic responses
associated with short-term high-fat overfeeding. To this end, four separate studies are …

Endurance trained athletes (Trained) and type 2 diabetes (T2DM) patients have similar
intramyocellular lipid (IMCL) content, but differ in levels of insulin sensitivity; the so-called …

Résumé Aujourd'hui encore, l'obésité touche de plus en plus d'individus, et sa complexité
reflète son aspect multifactoriel. Parmi les facteurs impliqués dans le développement de …

Increased intracellular lipid content in cardiac muscle is observed in pathological conditions
like ischemia and type 2 diabetes (T2DM). This can result in lipotoxic events which …