Comparing stroke and bleeding with rivaroxaban and dabigatran in atrial fibrillation: analysis of the US Medicare Part D data

I Hernandez, Y Zhang - American Journal of Cardiovascular Drugs, 2017 - Springer
Background No studies have directly compared the effectiveness and safety of dabigatran
and rivaroxaban using US Medicare data. Objective Our objective was to compare …

Adherence to rivaroxaban, dabigatran, and apixaban for stroke prevention for newly diagnosed and treatment-naive atrial fibrillation patients: an update using 2013 …

JD Brown, AR Shewale, JC Talbert - Journal of managed care & specialty …, 2017 - jmcp.org
BACKGROUND: Few studies have assessed adherence to non-vitamin K antagonist oral
anticoagulants (NOACs), especially using contemporary data now that multiple NOACs are …

Bleeding risk of apixaban, dabigatran, and low-dose rivaroxaban compared with warfarin in Japanese patients with non-valvular atrial fibrillation: a propensity …

S Kohsaka, T Murata, N Izumi, J Katada… - … medical research and …, 2017 - Taylor & Francis
Objectives: There is scarce evidence comparing novel oral anticoagulants (NOACs) with
warfarin in real-world settings in Japan. This study compared the risk of bleeding events …

Safety profile of the direct oral anticoagulants: an analysis of the WHO database of adverse drug reactions

L Monaco, C Biagi, V Conti, M Melis… - British journal of …, 2017 - Wiley Online Library
Aim Direct oral anticoagulants (DOACs) have shown noninferiority to warfarin for stroke
prevention in nonvalvular atrial fibrillation (AF) and a more promising safety profile …

Efficacy and safety of the target-specific oral anticoagulants for stroke prevention in atrial fibrillation: the real-life evidence

V Russo, A Rago, R Proietti, F Di Meo… - … Advances in Drug …, 2017 - journals.sagepub.com
The aim of our article is to provide a concise review for clinicians entailing the main studies
that evaluated the efficacy and safety of target-specific oral anticoagulants (TSOAs) for …

Management and outcome of gastrointestinal bleeding in patients taking oral anticoagulants or antiplatelet drugs

S Pannach, J Goetze, S Marten, T Schreier… - Journal of …, 2017 - Springer
Background Non-vitamin K dependent oral anticoagulants (NOACs) significantly decrease
overall major bleeding rates compared with vitamin K antagonists (VKAs) but there is …

Risk of major bleeding in patients with non-valvular atrial fibrillation treated with oral anticoagulants: a systematic review of real-world observational studies

S Deitelzweig, C Farmer, X Luo, L Vo, X Li… - Current Medical …, 2017 - Taylor & Francis
Objective: To conduct a systematic review of real-world (RWD) studies comparing the risk of
major bleeding (MB) among patients with non-valvular atrial fibrillation (NVAF) on direct oral …

Permanent discontinuation of non vitamin K oral anticoagulants in real life patients with non-valvular atrial fibrillation

MC Vedovati, P Verdecchia, M Giustozzi… - International Journal of …, 2017 - Elsevier
Background Persistence to treatment affects clinical outcomes in patients with chronic
disease such as atrial fibrillation (AF). Methods This prospective cohort study included …

Management and outcomes of bleeding events in patients in the emergency department taking warfarin or a non–vitamin k antagonist oral anticoagulant

AJ Singer, A Quinn, N Dasgupta… - The Journal of emergency …, 2017 - Elsevier
Background Most comparisons of bleeding patients who are taking warfarin or a non–
vitamin K oral anticoagulant (NOAC) have been limited to admitted patients and major …

Scoring systems for estimating the risk of anticoagulant-associated bleeding

AL Parks, MC Fang - Seminars in thrombosis and hemostasis, 2017 - thieme-connect.com
Anticoagulant medications are frequently used to prevent and treat thromboembolic disease.
However, the benefits of anticoagulants must be balanced with a careful assessment of the …