Micro-and nano-patterned elastin-like polypeptide hydrogels for stem cell culture

A Paul, M Stührenberg, S Chen, D Rhee, WK Lee… - Soft Matter, 2017 - pubs.rsc.org
We show that submicron-sized patterns can be imprinted into soft, recombinant-engineered
protein hydrogels (here elastin-like proteins, ELP) by transferring wavy patterns from …

A bioartificial environment for kidney epithelial cells based on a supramolecular polymer basement membrane mimic and an organotypical culture system

BB Mollet, ILJ Bogaerts, GC van Almen… - Journal of Tissue …, 2017 - Wiley Online Library
Renal applications in healthcare, such as renal replacement therapies and nephrotoxicity
tests, could potentially benefit from bioartificial kidney membranes with fully differentiated …

Light-responsive polymer brushes: Active topographic cues for cell culture applications

RH Kollarigowda, C Fedele, C Rianna, A Calabuig… - Polymer …, 2017 - pubs.rsc.org
In the call for novel stimuli-responsive biomaterials, azobenzene-containing polymer
brushes entail a remarkable potential. In fact, their ability to be patterned at the micro-and …

Deterministic integration of biological and soft materials onto 3D microscale cellular frameworks

JM McCracken, S Xu, A Badea, KI Jang… - Advanced …, 2017 - Wiley Online Library
Complex 3D organizations of materials represent ubiquitous structural motifs found in the
most sophisticated forms of matter, the most notable of which are in life‐sustaining …

Surface nanotopography guides kidney-derived stem cell differentiation into podocytes

M MacGregor-Ramiasa, I Hopp, A Bachhuka, P Murray… - Acta biomaterialia, 2017 - Elsevier
Stem cells have enormous potential for developing novel therapies for kidney disease but
our current inability to direct their differentiation to specialised renal cells presents a barrier …

Augmenting the bioactivity of polyetheretherketone using a novel accelerated neutral atom beam technique

S Ajami, MJ Coathup, J Khoury… - Journal of Biomedical …, 2017 - Wiley Online Library
Polyetheretherketone (PEEK) is an alternative to metallic implants in orthopedic
applications; however, PEEK is bioinert and does not osteointegrate. In this study, an …

Mechanical properties and fatigue analysis on poly (ε-caprolactone)-polydopamine-coated nanofibers and poly (ε-caprolactone)-carbon nanotube composite scaffolds

J Fernández, O Auzmendi, H Amestoy… - European Polymer …, 2017 - Elsevier
Recent trends in tissue engineering have focused on the development of electrically
conductive composite scaffolds (ie with carbon nanotubes) and on increasing the cell …

Polymeric mechanical amplifiers of immune cytokine-mediated apoptosis

MJ Mitchell, J Webster, A Chung… - Nature …, 2017 - nature.com
Physical forces affect tumour growth, progression and metastasis. Here, we develop
polymeric mechanical amplifiers that exploit in vitro and in vivo physical forces to increase …

Flexible gold nanocone array surfaces as a tool for regulating neuronal behavior

M Toma, A Belu, D Mayer, A Offenhäusser - Small, 2017 - Wiley Online Library
Accelerated neurite outgrowth of rat cortical neurons on a flexible and inexpensive substrate
functionalized with gold nanocone arrays is reported. The gold nanocone arrays are …

Facile endothelium protection from TNF-α inflammatory insult with surface topography

G Stefopoulos, C Giampietro, V Falk, D Poulikakos… - Biomaterials, 2017 - Elsevier
Adverse events triggered by the direct contact between blood and synthetic materials
constitute a sincere shortcoming of cardiovascular implant technology. A well-connected …