Background Optimization of the differentiation medium through using autologous factors
such as PRP is of great consideration, but due to the complex, variable and undefined …

Vascular endothelial growth factor (VEGF) is associated with tumour growth and metastasis.
Because VEGF is the major player in both angiogenesis and vascular permeability and the …

Background Although sorafenib is the only available drug with proven efficacy for patients
with advanced hepatocellular carcinoma (HCC), the clinical efficacy of sorafenib is variable …

Vasculogenesis and angiogenesis are the processes by which new blood vessels are
formed. We have developed a serum-free human adipose stromal cell and umbilical cord …

Small-molecule multitargeted tyrosine kinase inhibitor (TKI) therapy is used in different types
of cancer. These drugs have been associated with cardiovascular toxicity, including aortic …

Urothelial cell carcinoma (UCC) of the bladder comprises a mixture of heterogeneous tumor
cell populations, the surrounding stroma (which is populated by different types of …

Alternative splicing of mRNA leads to an increase in proteome biodiversity by allowing the
generation of multiple mRNAs, coding for multiple protein isoforms of various structural and …

Objective: The antitumor effect of ciprofloxacin has been widely assessed in-vitro, and
positive results have been reported. The aim of this study was to investigate the influence of …

Pulmonary arterial hypertension (PAH) has been frequently compared with a type of
malignant disease and has an incredible number of pathogenic mechanisms similar to …

Hepatocellular carcinoma (HCC) is the vital cause of cancer-related death throughout the
world. At present, the exact mechanism responsible for the formation of HCC and its …