Bipolar disorder and immune dysfunction: epidemiological findings, proposed pathophysiology and clinical implications
JD Rosenblat, RS McIntyre - Brain sciences, 2017 - mdpi.com
Bipolar disorder (BD) is strongly associated with immune dysfunction. Replicated
epidemiological studies have demonstrated that BD has high rates of inflammatory medical …
epidemiological studies have demonstrated that BD has high rates of inflammatory medical …
Bipolar disorder and inflammation
JD Rosenblat, RS McIntyre - Psychiatric Clinics, 2016 - psych.theclinics.com
Methods For this narrative clinical overview, the MEDLINE/PubMed, Embase, Google
Scholar and ClinicalTrials. gov databases were searched from inception through June 2015 …
Scholar and ClinicalTrials. gov databases were searched from inception through June 2015 …
The immunology of bipolar disorder
IG Barbosa, R Machado-Vieira, JC Soares… - …, 2014 - karger.com
Bipolar disorder (BD) is a psychiatric condition associated with elevated frequency of clinical
comorbidities and cognitive impairment. The neurobiology of BD is not completely …
comorbidities and cognitive impairment. The neurobiology of BD is not completely …
Monocyte and lymphocyte activation in bipolar disorder: a new piece in the puzzle of immune dysfunction in mood disorders
IG Barbosa, NP Rocha, F Assis… - International Journal …, 2015 - academic.oup.com
Background: This study tested the hypothesis that the low-grade inflammation presented in
patients with bipolar disorder (BD) is associated with expansion of activated T cells, and this …
patients with bipolar disorder (BD) is associated with expansion of activated T cells, and this …
Neuroinflammation in bipolar depression
F Benedetti, V Aggio, ML Pratesi, G Greco… - Frontiers in …, 2020 - frontiersin.org
Bipolar disorder (BD) is a leading cause of worldwide disability among mood disorders.
Pathological mechanisms are still vastly unclear, and current treatments with conventional …
Pathological mechanisms are still vastly unclear, and current treatments with conventional …
Revisiting inflammation in bipolar disorder
Bipolar disorder (BD) has been associated with immune changes, and yet their underlying
mechanisms are still not fully understood. Here, we review the current state of the field …
mechanisms are still not fully understood. Here, we review the current state of the field …
Medical comorbidity in bipolar disorder: the link with metabolic-inflammatory systems
A SayuriYamagata, E Brietzke, JD Rosenblat… - Journal of Affective …, 2017 - Elsevier
Background Bipolar disorder (BD) is associated with chronic low-grade inflammation,
several medical comorbidities and a decreased life expectancy. Metabolic-inflammatory …
several medical comorbidities and a decreased life expectancy. Metabolic-inflammatory …
Are medical comorbid conditions of bipolar disorder due to immune dysfunction?
JD Rosenblat, RS McIntyre - Acta Psychiatrica Scandinavica, 2015 - Wiley Online Library
Objective Epidemiological data have shown a clear association between bipolar disorder
(BD) and medical comorbidities. The aim of this article was to assess the evidence of …
(BD) and medical comorbidities. The aim of this article was to assess the evidence of …
Inflammation as a neurobiological substrate of cognitive impairment in bipolar disorder: evidence, pathophysiology and treatment implications
JD Rosenblat, E Brietzke, RB Mansur… - Journal of affective …, 2015 - Elsevier
Background Bipolar disorder (BD) has been associated with cognitive impairment during
depressed, manic and euthymic periods. Inflammation has been shown to be involved in the …
depressed, manic and euthymic periods. Inflammation has been shown to be involved in the …
Immunity, inflammation, and bipolar disorder: diagnostic and therapeutic implications
N Hamdani, R Doukhan, O Kurtlucan… - Current psychiatry …, 2013 - Springer
Bipolar disorder is now known to be associated not only with highly prevalent co-occurring
psychiatric and substance use disorders but also with medical comorbidities, such as …
psychiatric and substance use disorders but also with medical comorbidities, such as …
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