Cadexomer iodine provides superior efficacy against bacterial wound biofilms in vitro and in vivo

DJ Fitzgerald, PJ Renick, EC Forrest… - Wound repair and …, 2017 - Wiley Online Library
Examination of clinical samples indicates bacterial biofilms are present in the majority of
chronic wounds, and substantial evidence suggests biofilms contribute significantly to …

Cadexomer iodine effectively reduces bacterial biofilm in porcine wounds ex vivo and in vivo

ED Roche, EJ Woodmansey, Q Yang… - International wound …, 2019 - Wiley Online Library
Biofilms are prevalent in non‐healing chronic wounds and implicated in delayed healing.
Tolerance to antimicrobial treatments and the host's immune system leave clinicians with …

In vitro comparison of antimicrobial activity of iodine and silver dressings against biofilms

RMS Thorn, AJ Austin, J Greenman… - Journal of wound …, 2009 - magonlinelibrary.com
Objective: To compare the antimicrobial effectiveness of silver-and iodine-containing wound
dressings against preformed mature biofilms of pathogenic wound bacteria grown in vitro …

Assessment of Cadexomer Iodine against Staphylococcus aureus Biofilm In vivo and In vitro Using Confocal Laser Scanning Microscopy

H Akiyama, T Oono, M Saito… - The Journal of …, 2004 - Wiley Online Library
Abstract Cadexomer iodine releases iodine (0.9% weight/weight) slowly from beads of
dextrin and epichlorhydrin. This preparation is an effective debridement and antiseptic agent …

An in vitro model of chronic wound biofilms to test wound dressings and assess antimicrobial susceptibilities

KE Hill, S Malic, R McKee, T Rennison… - Journal of …, 2010 - academic.oup.com
Objectives The targeted disruption of biofilms in chronic wounds is an important treatment
strategy and the subject of intense research. In the present study, an in vitro model of chronic …

Controlled‐release iodine foam dressings demonstrate broad‐spectrum biofilm management in several in vitro models

AM Salisbury, M Mullin, L Foulkes… - International Wound …, 2022 - Wiley Online Library
Multiple in vitro models were utilised to evaluate the biofilm management capabilities of
seven commercially‐available wound dressings, varying in composition and antibacterial …

Assessing the effect of an antimicrobial wound dressing on biofilms

SL Percival, P Bowler, EJ Woods - Wound repair and …, 2008 - Wiley Online Library
To date the effect of silver‐containing wound dressings on biofilms, known to be present in
chronic wounds, has not been determined or documented. In this current study, we aimed to …

In vitro Activity of Antimicrobial Wound Dressings on P. aeruginosa Wound Biofilm

EK Stuermer, I Plattfaut, M Dietrich, F Brill… - Frontiers in …, 2021 - frontiersin.org
The treatment of acute and chronic infected wounds with residing biofilm still poses a major
challenge in medical care. Interactions of antimicrobial dressings with bacterial load, biofilm …

Biofilms and delayed healing–an in vitro evaluation of silver‐and iodine‐containing dressings and their effect on bacterial and human cells

KA Bourdillon, CP Delury… - International Wound …, 2017 - Wiley Online Library
This study investigated whether there are differences in the ability of wound dressings to
modulate certain factors known to affect wound healing. A selection of antimicrobial …

Inhibition of Pseudomonas aeruginosa biofilm formation on wound dressings

KS Brandenburg, DF Calderon… - Wound Repair and …, 2015 - Wiley Online Library
Chronic nonhealing skin wounds often contain bacterial biofilms that prevent normal wound
healing and closure and present challenges to the use of conventional wound dressings …