Novel series of phthalazine derivatives 6–11 were designed, synthesized, and evaluated for
their anticancer activity against two human tumor cell lines, HCT‐116 human colon …

In the designed compounds, a new linker was inserted in the form of fragments with verified
VEGFR‐2 inhibitory potential, including an α, β‐unsaturated ketonic fragment, pyrazole, and …

Abstract Twenty new N‐substituted‐4‐phenylphthalazin‐1‐amine derivatives were
designed, synthesized, and evaluated for their anticancer activities against HepG2, HCT …

In accordance with the significant impetus of the discovery of potent vascular endothelial
growth factor receptor 2 (VEGFR‐2) inhibitors, herein, we report the design, synthesis, and …

Abstract Novel pyridine‐derived compounds (5–19) were designed and synthesized, and
their anticancer activities were evaluated against HepG2 and MCF‐7 cells, targeting the …

In our endeavor towards the development of effective VEGFR-2 inhibitors, three novel series
of phthalazine derivatives based on 1-piperazinyl-4-arylphthalazine scaffold were …

The anticancer activity of novel thiazolidine‐2, 4‐diones was evaluated against HepG2, HCT‐
116, and MCF‐7 cells. MCF‐7 was the most sensitive cell line to the cytotoxicity of the new …

A novel series of 1‐benzylquinazoline‐2, 4 (1H, 3H)‐dione derivatives, 6a, b to 11a–e, was
designed, synthesized, and evaluated for their anticancer activity against HepG2, HCT‐116 …

Novel phthalazine derivatives were designed, synthesized and evaluated against Hep G2
and MCF-7 as VEGFR-2 inhibitors. In particular, compounds 2g and 4a were found to be the …

A novel series of benzoxazole/benzothiazole derivatives 4a–c–11a–e were designed,
synthesized, and evaluated for anticancer activity against HepG2, HCT‐116, and MCF‐7 …