Calcium and zinc differentially affect the structure of lipid membranes

N Kučerka, E Dushanov, KT Kholmurodov… - Langmuir, 2017 - ACS Publications
Interactions of calcium (Ca2+) and zinc (Zn2+) cations with biomimetic membranes made of
dipalmitoylphosphatidylcholine (DPPC) were studied by small angle neutron diffraction …

[HTML][HTML] Interaction of small ionic species with phospholipid membranes: The role of metal coordination

CTM Le, A Houri, N Balage, BJ Smith… - Frontiers in Materials, 2019 - frontiersin.org
In studies of the transfer, distribution and biochemical activity of metal ions it is typically
assumed that the phospholipid bilayer acts as an inert barrier. Yet, there is mounting …

Swelling of phospholipid membranes by divalent metal ions depends on the location of the ions in the bilayers

RJ Alsop, RM Schober, MC Rheinstädter - Soft Matter, 2016 - pubs.rsc.org
The Hofmeister series illustrates how salts produce a wide range of effects in biological
systems, which are not exclusively explained by ion charge. In lipid membranes, charged …

Cation–zwitterionic lipid interactions are affected by the lateral area per lipid

N Kučerka, E Ermakova, E Dushanov… - Langmuir, 2020 - ACS Publications
Interactions of the divalent cations Ca2+ and Mg2+ with the zwitterionic lipid bilayers
prepared of a fully saturated dipalmitoylphosphatidylcholine (DPPC) or a di …

Two cations, two mechanisms: interactions of sodium and calcium with zwitterionic lipid membranes

M Javanainen, A Melcrová, A Magarkar… - Chemical …, 2017 - pubs.rsc.org
Adsorption of metal cations onto a cellular membrane changes its properties, such as
interactions with charged moieties or the propensity for membrane fusion. It is, however …

Calcium adsorption and displacement: characterization of lipid monolayers and their interaction with membrane-active peptides/proteins

SO Hagge, MU Hammer, A Wiese, U Seydel… - BMC biochemistry, 2006 - Springer
Background The first target of antimicrobial peptides (AMPs) is the bacterial membrane. In
the case of Gram-negative bacteria this is the outer membrane (OM), the lipid composition of …

Spectroscopic evidence for hydration and dehydration of lipid bilayers upon interaction with metal ions: a new physical insight

SK De, N Kanwa, M Ahamed… - Physical Chemistry …, 2018 - pubs.rsc.org
In this manuscript, we investigate the interactions of different metal ions with zwitterionic
phospholipid bilayers of different chain lengths using the well-known membrane probe …

Structural changes in dipalmitoylphosphatidylcholine bilayer promoted by Ca2+ ions: a small-angle neutron scattering study

D Uhríková, N Kučerka, J Teixeira, V Gordeliy… - Chemistry and physics …, 2008 - Elsevier
Small-angle neutron scattering (SANS) curves of unilamellar dipalmitoylphosphatidylcholine
(DPPC) vesicles in 1–60mM CaCl2 were analyzed using a strip-function model of the …

Study of the effect of Na+ and Ca2+ ion concentration on the structure of an asymmetric DPPC/DPPC+ DPPS lipid bilayer by molecular dynamics simulation

RD Porasso, JJL Cascales - Colloids and Surfaces B: Biointerfaces, 2009 - Elsevier
A molecular dynamics simulation study of the steady and dynamic properties of an
asymmetric phospholipid bilayer was carried out in the presence of sodium or calcium ions …

Effects of Na+, K+, and Ca2+ on the Structures of Anionic Lipid Bilayers and Biological Implication

H Yang, Y Xu, Z Gao, Y Mao, Y Du… - The Journal of Physical …, 2010 - ACS Publications
Ion− membrane interactions are essential to the regulation of cell functions. While numerous
molecular dynamics (MD) simulations have been carried out to study the effects of ions on …