B cells from patients with multiple sclerosis induce cell death via apoptosis in neurons in vitro
RP Lisak, L Nedelkoska, JA Benjamins… - Journal of …, 2017 - Elsevier
B cells mediate multiple sclerosis (MS) pathogenesis by mechanisms unrelated to
immunoglobulin (Ig). We reported that supernatants (Sup) from cultured B cells from blood of …
immunoglobulin (Ig). We reported that supernatants (Sup) from cultured B cells from blood of …
Secretory products of multiple sclerosis B cells are cytotoxic to oligodendroglia in vitro
RP Lisak, JA Benjamins, L Nedelkoska… - Journal of …, 2012 - Elsevier
B cells are important in the pathogenesis of multiple sclerosis (MS) and some of the effects
are not dependent on maturation of B cells into immunoglobulin (Ig) producing plasmablasts …
are not dependent on maturation of B cells into immunoglobulin (Ig) producing plasmablasts …
Role of B cells in pathogenesis of multiple sclerosis
B Nikbin, MM Bonab, F Khosravi, F Talebian - International review of …, 2007 - Elsevier
Despite the current limited understanding of the etiology of multiple sclerosis (MS), genetic
susceptibility and environmental influences are known driving factors. MS is considered a T …
susceptibility and environmental influences are known driving factors. MS is considered a T …
[HTML][HTML] Identification of a B cell-dependent subpopulation of multiple sclerosis by measurements of brain-reactive B cells in the blood
S Kuerten, G Pommerschein, SK Barth, C Hohmann… - Clinical …, 2014 - Elsevier
B cells are increasingly coming into play in the pathogenesis of multiple sclerosis (MS).
Here, we screened peripheral blood mononuclear cells (PBMC) from patients with clinically …
Here, we screened peripheral blood mononuclear cells (PBMC) from patients with clinically …
B cells and antibodies in CNS demyelinating disease
AH Cross, JL Trotter, JA Lyons - Journal of neuroimmunology, 2001 - Elsevier
There is much evidence to implicate B cells, plasma cells, and their products in the
pathogenesis of MS. Despite unequivocal evidence that the animal model for MS, EAE, is …
pathogenesis of MS. Despite unequivocal evidence that the animal model for MS, EAE, is …
Antibodies produced by clonally expanded plasma cells in multiple sclerosis cerebrospinal fluid cause demyelination of spinal cord explants
K Blauth, J Soltys, A Matschulat, CR Reiter… - Acta …, 2015 - Springer
B cells are implicated in the etiology of multiple sclerosis (MS). Intrathecal IgG synthesis,
cerebrospinal fluid (CSF) oligoclonal bands and lesional IgG deposition suggest a role for …
cerebrospinal fluid (CSF) oligoclonal bands and lesional IgG deposition suggest a role for …
B-cell differentiation in the CNS of patients with multiple sclerosis
A Corcione, F Aloisi, B Serafini, E Capello… - Autoimmunity …, 2005 - Elsevier
Clonally expanded populations of Ig variable gene-mutated B cells are found in the central
nervous system (CNS) of subjects with multiple sclerosis (MS), suggesting the occurrence of …
nervous system (CNS) of subjects with multiple sclerosis (MS), suggesting the occurrence of …
B cells in multiple sclerosis: connecting the dots
Over the past two decades B cells have increasingly moved into the spotlight in multiple
sclerosis (MS) research. This interest was fuelled by growing understanding and acceptance …
sclerosis (MS) research. This interest was fuelled by growing understanding and acceptance …
[PDF][PDF] Potential role of humoral immunity in the pathogenesis of multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE)
M del Pilar Martin, NL Monson - Front Biosci, 2007 - article.imrpress.com
[Frontiers in Bioscience 12, 2735-2749, January 1, 2007] 2735 Potential Role of Humoral
Immunity in the Pathogenesis of Multipl Page 1 [Frontiers in Bioscience 12, 2735-2749, January …
Immunity in the Pathogenesis of Multipl Page 1 [Frontiers in Bioscience 12, 2735-2749, January …
B cells and autoantibodies in the pathogenesis of multiple sclerosis and related inflammatory demyelinating diseases
KA McLaughlin, KW Wucherpfennig - Advances in immunology, 2008 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system (CNS). The mainstream view is that MS is caused by an autoimmune attack …
nervous system (CNS). The mainstream view is that MS is caused by an autoimmune attack …