Safety evaluation of auraptene in rats in acute and subacute toxicity studies

T Vakili, M Iranshahi, H Arab, B Riahi… - Regulatory Toxicology …, 2017 - Elsevier
Auraptene (AUR) is a natural, bioactive, monoterpene coumarin ether. It has anti-
inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective …

[HTML][HTML] Comparative analysis of the cytotoxic effect of 7-prenyloxycoumarin compounds and herniarin on MCF-7 cell line

SH Mousavi, AS Davari, M Iranshahi… - Avicenna Journal of …, 2015 - ncbi.nlm.nih.gov
Objective: 7-prenyloxycoumarins are a group of secondary metabolites that are found mainly
in plants belonging to the Rutaceae and Umbelliferae families. This study was designed to …

[HTML][HTML] Cytotoxic effects of auraptene against a human malignant glioblastoma cell line

AR Afshari, MK Roshan, M Soukhtanloo… - Avicenna journal of …, 2019 - ncbi.nlm.nih.gov
Objective: Glioblastoma multiforme (GBM) is the deadliest type of primary brain tumors, and
the survival of patients is estimated to be only about one year. This study, for the first time …

A review of the pharmacological and therapeutic effects of auraptene

B Bibak, F Shakeri, GE Barreto, Z Keshavarzi… - Biofactors, 2019 - Wiley Online Library
There is a growing awareness in herbal medications as they are usually safe and devoid of
significant adverse effects. Auraptene is a natural bioactive monoterpene coumarin ether …

[HTML][HTML] A review of auraptene as an anticancer agent

Z Tayarani-Najaran, N Tayarani-Najaran… - Frontiers in …, 2021 - frontiersin.org
Auraptene is a bioactive monoterpene coumarin isolated from Citrus aurantium and Aegle
marmelos that belong to the Rutaceae family. Auraptene can modulate intracellular …

Anti-oxidant and anti-inflammatory effects of auraptene on phytohemagglutinin (PHA)-induced inflammation in human lymphocytes

VR Askari, VB Rahimi, R Zargarani, R Ghodsi… - Pharmacological …, 2021 - Springer
Background Inflammation is characterized as a defensive response of our body against
endogenous or exogenous stimuli. Chronic inflammation and oxidative stress play an …

Anti-Inflammatory Effect of Auraptene Extracted from Trifoliate Orange (Poncirus Trifoliate) on LPS-Stimulated RAW 264.7 Cells

H Yan, Z Ma, S Peng, X Deng - Inflammation, 2013 - Springer
Poncirus trifoliate is a traditional Chinese medicinal plant used for treating inflammation-
related diseases for a long time and trifoliate orange contains abundant auraptene. The …

Auraptene: a natural biologically active compound with multiple targets

S Genovese, F Epifano - Current Drug Targets, 2011 - ingentaconnect.com
Auraptene is the most abundant prenyloxycoumarin that occurs in nature. It has been
isolated from plants belonging to many genus of the Rutaceae family, comprising several …

Neuroprotective effects of auraptene following traumatic brain injury in male rats: The role of oxidative stress

Z Keshavarzi, S Amiresmaili, N Shahrokhi, B Bibak… - Brain research …, 2021 - Elsevier
Abstract Aim Traumatic Brain Injury (TBI) is widely acknowledged as a significant risk factor
for death and disability. Our goal in this experiment was to see if Auraptene (AUR) could …

Acute toxicity study of the ethanolic extract of Eleutherine bulbosa Urb in Wistar rats

H Wati, R Muthia, K Kartini… - Pharmacy Education, 2021 - repository.ubaya.ac.id
Introduction: Eleutherine bulbosa Urb is a plant species with medicinal properties, including
anti-inflammatory, widely relied upon in traditional practices. For this reason, the present …